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UPDATED: Nov 16, 2025

Stock Analysis

Neurogene
NASDAQ:NGNE
$22.77
-$3.72 |-14.04%
Day Range:
$22.43 - $27.64
Market Cap:
324.97M
P/E Ratio:
0.0000
Avg Value:
$22.07
Year Range:
$6.88 - $37.27
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General Information
Neurogene Inc is a clinical-stage biotechnology company committed to overcoming the limitations of neurological diseases into treatable conditions, by harnessing its proprietary transgene regulation technology, EXACTTM (Expression Attenuation via Construct Tuning).

It is building a differentiated product portfolio of genetic medicines for rare neurological diseases with high unmet needs. The drug candidates in the company's product pipeline include NGN-401, which is in development for the treatment of Rett syndrome, using its EXACT platform, and NGN-101, a non-EXACT, conventional gene therapy development candidate for the treatment of CLN5 Batten disease, designed to deliver the CLN5 gene and packaged in an AAV9 capsid.

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Neurogene (NGNE) Stock Graph
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How We Grade Neurogene (NGNE)

We grade stocks based on past performance, their future growth potential, intrinsic value, dividend history, and overall financial health.

The chart below shows how we grade Neurogene (NGNE) across the board compared to its closest peers.

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Benzinga Edge Rankings

Benzinga Edge stock rankings give you four critical scores to help you identify the strongest and weakest stocks to buy and sell.

Momentum measures a stock's relative strength based on its price movement patterns and volatility over multiple timeframes, ranked as a percentile against other stocks.

Stock Score Locked: Want to See it?
Benzinga Rankings give you vital metrics on any stock – anytime.
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Peer Ratings

See how Neurogene compares to its peers in these key performance metrics from Benzinga Rankings.

Top Peers
Value
Quality
Growth
Momentum
Short
Medium
Long
TECXTectonic Therapeutic
0
0
0
8.9
SLDBSolid Biosciences
0
0
0
77.08
TRDAEntrada Therapeutics
0
0
0
14.64
PEPGPepGen
0
0
0
95.71
Short: price trend over the last couple of months
Medium: price trend over the last couple of quarters
Long: price trend over the past year
Stock Score Locked: Want to See it?
Benzinga Rankings give you vital metrics on any stock – anytime.
6
Future Growth
Our estimate of future price growth is based on an aggregation of 3 analyst ratings over the past 3 months and their 12-month price targets.

Below, you can see that analysts are estimating a 12-month price target range of $45.00 - $70.00 with an average of $60.00

163.50%
Expected movement for Neurogene (NGNE) over the next 12 months
Based on these rankings

Recent Ratings for Neurogene (NGNE)

HC Wainwright & Co.
Date:
Nov 13, 2025
Action:
Maintains
Prev. Target:
$65.00
New Target:
$70.00
HC Wainwright & Co.
Date:
Oct 31, 2025
Action:
Maintains
Prev. Target:
$45.00
New Target:
$65.00
HC Wainwright & Co.
Date:
Oct 9, 2025
Action:
Reiterates
Prev. Target:
$45.00
New Target:
$45.00
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Past Performance
How has Neurogene (NGNE) performed over the past 5 years?

The two main factors that we consider when analyzing past performance is overall return and volatility

Using these two metrics, we can determine if this stock gave its investors enough return for the risk that they took on by owning it. This is measured by the sharpe ratio, which has been used as a primary measure of risk/reward trade-off for almost 60 years.

This ratio can be interpreted as the amount of return an investor has received for the amount of risk that they took on by owning the stock over that timeframe.

Neurogene (NGNE) sharpe ratio over the past 5 years is 0.2813 which is considered to be above average compared to the peer average of -0.3977