Tema GLP-1, Obesity & Cardiometabolic ETF (NASDAQ: HRTS) prezzo delle azioni, notizie, grafici, ricerca sulle azioni, profilo.

Tema GLP-1, Obesity & Cardiometabolic ETF (NASDAQ:HRTS) Citazioni e riassunti delle notizie

Healthcare

Other

TEMA ETFs

The investment seeks to provide long-term growth of capital by investing in companies leading the fight against diabetes, obesity and cardiovascular diseases. Obesity is on the cusp of a revolution in therapeutics, while heart disease, the most common cause of death, is witnessing a renaissance of therapies driven by genetic insights and tools.

Tema Cardiovascular and Metabolic ETF

Tema GLP-1, Obesity & Cardiometabolic ETF

<a href="https://www.whitehouse.gov/briefing-room/statements-releases/2024/11/01/statement-from-president-joe-biden-on-the-october-2024-jobs-report/" title="https://www.whitehouse.gov/briefing-room/statements-releases/2024/11/01/statement-from-president-joe-biden-on-the-october-2024-jobs-report/">https://www.whitehouse.gov/briefing-room/statements-releases/2024/11/01/statement-from-president-joe-biden-on-the-october-2024-jobs-report/</a>

Macro Notification

News

General

Biden, Responding To October Jobs Data, Says Job Growth Is Expected To Rebound In November; Adds ' There's More Work To Do'; Says Hurricanes, Strike Activity Lowered Job Growth

On Thursday, ESSA Pharma Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/EPIX#NASDAQ">EPIX</a>) announced its plans to terminate the Phase 2 trial of masofaniten combined with enzalutamide versus enzalutamide single agent in patients with metastatic castration-resistant prostate cancer (mCRPC) naïve to <a target="_blank" href="https://www.benzinga.com/pressreleases/24/10/n41669391/essa-pharma-announces-termination-of-phase-2-study-evaluating-masofaniten-combined-with-enzalutami" rel="noreferrer noopener">second-generation antiandrogens</a>.
This decision was based on a protocol-specified interim review of the safety, PK, and efficacy data, which showed a much higher rate of PSA90 response in patients treated with Pfizer Inc&#8217;s (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/PFE#NYSE">PFE</a>) Xtandi (enzalutamide) monotherapy (which is the standard of care for this patient population) than expected based on historical data.
In addition, there was no clear efficacy benefit seen with the combination of masofaniten plus enzalutamide compared to enzalutamide single agent.
A futility analysis determined a low likelihood of meeting the prespecified primary endpoint of the study.
The combination of masofaniten plus enzalutamide was well-tolerated with no new safety signals and a safety profile similar to that seen in Phase 1 studies.
&#8220;We made the difficult decision to terminate this Phase 2 study following the interim analysis because we concluded that the emerging efficacy profile of masofaniten combined with enzalutamide would not likely meet the primary endpoint of the study, nor our internal requirements for a prostate cancer therapy candidate,&#8221; said&nbsp;David Parkinson, President, and CEO.
As part of the effort to focus its resources, ESSA is also planning to terminate the other remaining company-sponsored and investigator-sponsored clinical studies evaluating masofaniten either as a monotherapy or in combination <a target="_blank" href="https://www.benzinga.com/pressreleases/24/09/n40862721/essa-pharma-presents-updated-phase-12-masofaniten-epi-7386-clinical-data-at-the-2024-esmo-congress" rel="noreferrer noopener">with other agents</a>.
As of&nbsp;September 30, 2024, the company had available cash reserves and short-term investments of&nbsp;$126.8 million&nbsp;and net working capital of&nbsp;$124.3 million.
In September, ESSA Pharma announced the presentation of updated dose escalation data from its Phase 1/2 study of masofaniten (formerly EPI-7386) in combination with enzalutamide at the 2024 European Society for Medical Oncology (ESMO) Congress.
Across all dose cohorts, 88% of patients (14 of 16) achieved PSA50, 88% of patients (14 of 16) achieved PSA90, 69% of patients (11 of 16) achieved PSA90 in less than 90 days, and 63% of patients (10 of 16) achieved PSA &lt;0.2ng/mL.
Price Action: EPIX stock was down 69.80% at $1.57 during the premarket session at the last check on Friday.
Read Next:
<ul>
<li><a href="https://www.benzinga.com/government/24/11/41685490/nvidias-run-ai-acquisition-draws-european-regulatory-scrutiny-on-competition-concerns" target="_blank" rel="noreferrer noopener">Nvidia&#8217;s Run: ai Acquisition Draws European Regulatory Scrutiny On Competition Concerns</a></li>
</ul>

Biotech

Health Care

Movers

EPIX

Cancer-Focused ESSA Pharma Ends Prostate Cancer Trial Due to Insufficient Efficacy From Combination Therapy

LyondellBasell Industries N.V. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/LYB#NYSE">LYB</a>) shares are trading lower after the company reported worse-than-expected <a target="_blank" href="https://www.benzinga.com/pressreleases/24/11/g41679038/lyondellbasell-reports-third-quarter-2024-earnings" rel="noreferrer noopener">third-quarter results</a>.
LYB reported revenues of $10.332 billion, down 2.8% year over year and missing the consensus of $10.601 billion.
Adjusted EBITDA stood at $1.21 billion (-14.1% Y/Y), and the margin contracted by 154 bps to 11.7%. Adjusted EPS stood at $1.88, <a target="_blank" href="https://www.benzinga.com/earnings" rel="noreferrer noopener">below the consensus of $1.98.</a>
North American polyethylene margins rose due to lower ethane and gas costs, with demand up over 7% year-to-date. High cracker operating rates boosted third-quarter&nbsp;ethylene volumes, while Europe and Asia margins benefited from lower feedstock costs.
LyondellBasell generated $670 million operating cash flow in the third quarter, with 80% cash conversion over 12 months.
The company invested $368 million in capital expenditures, returned $479 million to shareholders, and held $2.6 billion in cash with $7.3 billion in liquidity.
LyondellBasell&#8217;s CEO, Peter Vanacker, announced that the company started construction on its new MoReTec-1 facility in Germany, a key step toward a sustainable future.
Q4 Outlook: LyondellBasell anticipates softer demand in the fourth quarter due to seasonality, with sequentially higher natural gas and ethane feedstock&nbsp;costs likely impacting North American integrated&nbsp;polyolefins margins.
Operating rates are projected at 85% for North American O&amp;P assets, 60% for European O&amp;P, and 75% for I&amp;D assets, with easing interest rates expected to boost durable goods demand in 2025.
&#8220;Despite challenging global macroeconomic conditions, our strong North American operations allowed us to capitalize on favorable ethylene margins in the region,&#8221; said Vanacker.
Price Action: LYB shares traded lower by 0.98% at $86.00 premarket at the last check Friday.

Earnings

Equities

Guidance

LyondellBasell Q3 Results Miss Estimates, Signals Softer Demand And Rising Costs For Q4

Oppenheimer analyst Edward Yang maintains Onto Innovation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ONTO#NYSE">ONTO</a>) with a Outperform and raises the price target from $260 to $275.

Price Target

Analyst Ratings

ONTO

Oppenheimer Maintains Outperform on Onto Innovation, Raises Price Target to $275

Oppenheimer analyst Jed Kelly maintains LendingTree (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TREE#NASDAQ">TREE</a>) with a Outperform and raises the price target from $65 to $70.

TREE

Oppenheimer Maintains Outperform on LendingTree, Raises Price Target to $70

Keybanc analyst Alex Markgraff maintains Mastercard (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MA#NYSE">MA</a>) with a Overweight and raises the price target from $515 to $580.

Keybanc Maintains Overweight on Mastercard, Raises Price Target to $580

Oppenheimer analyst Leland Gershell maintains argenx (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ARGX#NASDAQ">ARGX</a>) with a Outperform and raises the price target from $560 to $646.

ARGX

Oppenheimer Maintains Outperform on argenx, Raises Price Target to $646

Oppenheimer analyst Michael Phillips maintains Hanover Insurance Gr (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/THG#NYSE">THG</a>) with a Outperform and raises the price target from $165 to $177.

Oppenheimer Maintains Outperform on Hanover Insurance Gr, Raises Price Target to $177

JP Morgan analyst Doug Anmuth maintains eBay (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/EBAY#NASDAQ">EBAY</a>) with a Neutral and lowers the price target from $60 to $58.

EBAY

JP Morgan Maintains Neutral on eBay, Lowers Price Target to $58

The U.S. Securities and Exchange Commission (SEC) announced Thursday that it has charged two affiliates of JPMorgan Chase &amp; Co. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/JPM#NYSE">JPM</a>) in five separate enforcement actions resulting in penalties and voluntary payments to investors of <a href="https://www.benzinga.com/markets/equities/24/10/41590849/jpmorgan-sues-customers-over-infinite-money-glitch-that-went-viral-on-tiktok-theyre-held-account">more than $151 million. </a>
The Details: The SEC<a href="https://www.sec.gov/newsroom/press-releases/2024-178"> charged</a> J.P. Morgan Securities LLC and J.P. Morgan Investment Management Inc. in five separate enforcement actions. Among the violations the agency flagged: misleading disclosures to investors, breach of fiduciary duty, prohibited joint transactions and principal trades, and failures to make recommendations in the best interest of customers. 
The JPMorgan affiliates agreed to pay more than $151 million in combined civil penalties and voluntary payments to investors to resolve the actions. The firm did not admit nor deny the findings in the SEC's orders. 
Read Next: <a href="https://www.benzinga.com/markets/asia/24/10/41656452/alibabas-strong-singles-day-sales-kickoff-hints-at-china-consumer-rebound">Alibaba&#8217;s Strong Singles&#8217; Day Sales Kickoff Hints At China Consumer Rebound</a>
"JPMorgan's conduct across multiple business lines violated various laws designed to protect investors from the risks of self-dealing and conflicts of interest," said Sanjay Wadhwa, Acting Director of the SEC's Division of Enforcement. 
"With today's settlements, which include multiple self-reports and large voluntary payments to harmed investors, JP Morgan is being held accountable for its regulatory failures," Wadhwa added.&nbsp;
One of the enforcement actions against J.P. Morgan Securities found that the firm made misleading disclosures to customers who invested in its Conduit private funds products which resulted in complaints from clients after the value of certain shares declined significantly.  
As part of the resolution, J.P. Morgan Securities agreed to make a voluntary payment of $90 million to more than 1,500 Conduit investor accounts. It also agreed to pay a civil penalty of $10 million, which will also be distributed to Conduit investors. 
Price Action: According to <a href="https://pro.benzinga.com/?gspk=YWRhbWVja2VydDUzMzY&amp;gsxid=zBMR4PKmcgBw">Benzinga Pro</a>, JPMorgan shares are up 0.09 % at $222.13 at the time of publication Friday.
Read Also:&nbsp;
<ul>
<li><a href="https://www.benzinga.com/news/24/10/41489239/bank-of-america-ceo-cautions-fed-not-to-go-too-fast-or-too-slow-on-interest-rate-cuts">Bank Of America CEO Cautions Fed Not To &#8216;Go Too Fast Or Too Slow&#8217; On Interest Rate Cuts</a></li>
</ul>
Image: Shutterstock&nbsp;

Large Cap

Legal

JPMorgan To Pay Investors $151 Million After SEC Flags 'Various Law Violations'

Oppenheimer analyst Ittai Kidron maintains Atlassian (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TEAM#NASDAQ">TEAM</a>) with a Outperform and raises the price target from $230 to $270.

TEAM

Oppenheimer Maintains Outperform on Atlassian, Raises Price Target to $270

JP Morgan analyst Tien-Tsin Huang maintains Mastercard (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MA#NYSE">MA</a>) with a Overweight and lowers the price target from $593 to $580.

JP Morgan Maintains Overweight on Mastercard, Lowers Price Target to $580

Keybanc analyst Justin Patterson maintains Uber Technologies (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/UBER#NYSE">UBER</a>) with a Overweight and lowers the price target from $90 to $85.

UBER

Keybanc Maintains Overweight on Uber Technologies, Lowers Price Target to $85

Oppenheimer analyst Jason Helfstein maintains Amazon.com (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMZN#NASDAQ">AMZN</a>) with a Outperform and raises the price target from $220 to $230.

AMZN

Oppenheimer Maintains Outperform on Amazon.com, Raises Price Target to $230

<ul>
<li>AMZN</li>
<li>INTC</li>
<li>NVDA</li>
<li>AAPL</li>
<li>DJT</li>
<li>SMCI</li>
<li>LOT</li>
<li>AMD</li>
<li>MSFT</li>
<li>META</li>
</ul>
Data from <a href="https://swaggystocks.com/dashboard/wallstreetbets/ticker-sentiment">https://swaggystocks.com/dashboard/wallstreetbets/ticker-sentiment</a>
&nbsp;

Trading Ideas

AAPL

INTC

MSFT

NVDA

SMCI

Top 10 Trending Stocks On WallStreetBets As Of November 1, 2024 (Via Swaggy Stocks)

Morgan Stanley analyst Terence Flynn maintains Merck &amp; Co (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MRK#NYSE">MRK</a>) with a Equal-Weight and lowers the price target from $130 to $123.

Morgan Stanley Maintains Equal-Weight on Merck & Co, Lowers Price Target to $123

NRIM

Northrim BanCorp Acquires Sallyport Commercial Finance In All Cash Transaction Valued At $53.9M

<a href="https://c212.net/c/link/?t=0&amp;l=en&amp;o=4292490-1&amp;h=325971108&amp;u=https%3A%2F%2Fwww.aon.com%2Fen%2F&amp;a=Aon+plc">Aon plc</a> (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AON#NYSE">AON</a>), a leading global professional services firm, today announced the signing of a definitive agreement to acquire UK-based insurance broker Griffiths &amp; Armour. Upon completion of the transaction, Griffiths &amp; Armour will become wholly-owned by Aon UK Limited and is proposed to go to market as "Griffiths &amp; Armour, an Aon company".
The acquisition closely aligns with Aon's strategy to further expand its presence in the UK and Ireland. The combination will provide a greater breadth of solutions for clients across both Aon and Griffiths &amp; Armour with complementary strengths that create a platform for further growth in the UK, Ireland and beyond. Together, Aon and Griffiths &amp; Armour share a strong cultural alignment through an unwavering focus on clients and colleagues.

Aon To Acquire UK-Based Insurance Broker Griffiths & Armour; Financial Terms Not Disclosed

Morgan Stanley analyst Lauren Schenk maintains Peloton Interactive (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PTON#NASDAQ">PTON</a>) with a Equal-Weight and raises the price target from $3.5 to $5.

PTON

Morgan Stanley Maintains Equal-Weight on Peloton Interactive, Raises Price Target to $5

Keybanc analyst Noah Zatzkin maintains Malibu Boats (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MBUU#NASDAQ">MBUU</a>) with a Overweight and raises the price target from $38 to $50.

MBUU

Keybanc Maintains Overweight on Malibu Boats, Raises Price Target to $50

HRTS: Exposure To GLP-1 Drug Developers Means Plenty Of Upside

HRTS: Generating Alpha In Obesity Treatment

Spiraling Obesity Costs Could Be Solved By Ozempic And Other Weight-Loss Drugs

The Case For Active Equity Investing: A Fund Manager's Perspective

ACTV

AFMC

AFSM

AMGN

ANEW

ARKK

ARKQ

ARTY

AVUV

BAPR

BOTZ

CYTK

DTEC

HRTS

IGPT

IVOO

IVOV

KOMP

LRNZ

MAGS

MREO

OZEM

ROBO

ROBT

SPLV

SPMD

SPMO

SPMV

SPSM

SPUS

SPUU

SPVM

SPVU

SPXE

SPXL

SPXN

SPXS

SPXT

SPXU

SPXV

SPYD

SPYG

SPYV

SPYX

SQEW

SQLV

SSPY

SVAL

SYLD

THNQ

THNR

TMDV

TPHD

TPLC

TPSC

UAUG

UBOT

UJAN

UMAR

UMAY

UOCT

UPRO

USMC

USMF

USVM

WTAI

Tema ETF Trust Tema Obesity & Cardiometabolic ETF

Learn About Cryptocurrency

acf/sidebar-related-posts

Learn about this leading blockchain platform that supports decentralized applications and smart contracts.

What is Ethereum?

Earning interest on your Ethereum is a great way to grow your cryptocurrency holdings. Find out how to earn interest on your Ethereum in 4 easy steps.

How to Earn Interest on Ethereum

Crypto continues to boom in 2024. Explore this list of the best cryptocurrencies to invest in this month. Start building your portfolio now!

10 Best Cryptocurrencies to Invest In for November 2024

10 Best Cryptocurrencies to Invest in for October 2024

Discover the best altcoins to invest in for high potential returns. Our top altcoin picks include Ethereum, Solana, Ripple, Dogecoin, Toncoin.

Top 10 Best Altcoins • Benzinga Crypto

10 Best Altcoins in November 2024

Top Cryptocurrency News

acf/news-feed

Cryptocurrency

Markets

$DOGE

$SHIB

Shytoshi Kusama Schools X User Who Said SHIB Will Remain 'Chump Change Meme' Unless It Can Rise Above A Penny: 'Those Who Are Wise Give Us Respect'

Analyst Color

$BTC

$ETH

$MATIC

$XRP

Harris Vs Trump: Crypto Industry Anticipates 'Favorable Regulatory Environment' For Bitcoin And Other Digital Assets After Elections

MSTR

Michael Saylor Says Bitcoin Remedy To Fix Unhealthy Balance Sheets As MicroStrategy Unveils Massive $42B BTC Purchase Plan

Politics

2024 Election Odds On Polymarket, Kalshi Show Trump Will Win: Why They Might Be Wrong

JD Vance's Interview With Joe Rogan Will Likely Mention The CIA, JFK And One Other Controversial Topic, Polymarket Traders Speculate

Future Finance Newsletter

acf/page-sidebar-placement

Cryptocurrency /Money Sidebar

Aperto	-
Alto	-
Massimo a 52 settimane	$36.03
AUM	67.50M
Dividendo	-
Data di stacco del dividendo	-
Volume	-
Capitalizzazione di mercato	$64.23B
Commissione di gestione	0.99%
Rapporto P/E	37.15
Chiusura precedente	$33.33
Basso	-
Minimo a 52 settimane	$26.26
Azioni in circolazione	-
Rendimento	-
Frequenza dei dividendi	-
Media Volume giornaliero	-
Beta	-
Media Rapporto di spesa	0.75%
Rapporto P/B	5.29

Aperto	-
Alto	-
Massimo a 52 settimane	$36.03
AUM	67.50M
Dividendo	-
Data di stacco del dividendo	-
Volume	-
Capitalizzazione di mercato	$64.23B
Commissione di gestione	0.99%
Rapporto P/E	37.15
Chiusura precedente	$33.33
Basso	-
Minimo a 52 settimane	$26.26
Azioni in circolazione	-
Rendimento	-
Frequenza dei dividendi	-
Media Volume giornaliero	-
Beta	-
Media Rapporto di spesa	0.75%
Rapporto P/B	5.29

Sector	Healthcare
Category	-
Investment Style	Large Cap Blend
Fund Inception	nov 20, 2023
Managers	Ryan Houlton Troy Cates Garrett Paolella Yuri Khodjamirian David Song
Definition	-

Comments

Tema GLP-1, Obesity & Cardiometabolic ETF

Panoramica

Tema GLP-1, Obesity & Cardiometabolic ETF (NASDAQ:HRTS) Citazioni e riassunti delle notizie

Notizie recenti

FAQ

ETF Details

Investment Policy

Notizie

PARTNER/COLLABORATORE

BENZINGA NEL MONDO