Lyra - LYR

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Lyra Therapeutics

Lyra Therapeutics Inc is a clinical-stage therapeutics company focused on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients. The Company's operations and manages its business as a single operating segment which is the business of developing targeted medicines to address ears, nose, and throat, or ENT diseases. Its initial product candidates, LYR-210 and LYR-220, are bioabsorbable polymeric matrices designed to be administered in a brief, non-invasive, in-office procedure and intended to deliver continuous drug therapy to the sinonasal passages for the treatment of chronic rhinosinusitis, or CRS.

Lyra Therapeutics Inc

U.S. stock futures slipped Thursday evening as tensions continued to flare in the Middle East, following Israel&#8217;s preemptive strike against Iran. 
Starting with the&nbsp;S&amp;P 500 Futures, which trades at 5,959.25, down 1.49%, followed by&nbsp;Nasdaq Futures&nbsp;at 21,580.25, down 1.59%, and&nbsp;Dow Jones Futures&nbsp;down 1.36%, trading at 42,404.00, at the time of writing this.
The futures markets dipped following Israel&#8217;s Defense Minister, Israel Katz declared a state of emergency, following the attack on Iran. Katz said, &#8220;Following the State of Israel's preemptive strike against Iran, a missile and drone attack against the State of Israel and its civilian population is expected in the immediate future,&#8221; according <a href="https://www.cnbc.com/2025/06/12/israels-defense-minister-announces-special-situation-after-israeli-attack-on-iran.html">to</a> CNBC.
On Wednesday, President Donald Trump announced that all non-emergency U.S. personnel located at its bases and embassies in the Middle East <a href="https://www.benzinga.com/markets/commodities/25/06/45897276/oil-etfs-surge-over-6-as-trump-orders-middle-east-evacuation-amid-iran-tensions-warns-region-could-be-dangerous">will be evacuated</a>, saying that it &#8220;could be a dangerous place.&#8221;
See Also: <a href="https://www.benzinga.com/news/politics/25/06/45916986/walmart-heiress-takes-on-trump-with-no-kings-ad-white-house-calls-it-burning-some-of-her-inheritance-for-a-pr-stunt">Walmart Heiress Takes On Trump With &#8216;No Kings&#8217; Ad: White House Calls It &#8216;Burning Some Of Her Inheritance For A PR Stunt&#8217;</a>
Secretary of State Marco Rubio issued a statement following Israel&#8217;s unilateral strikes, stating that the U.S. was not involved in the strikes against Iran and that the government&#8217;s top priority is protecting American troops in the region. &#8220;Let me be clear,&#8221; he said, &#8220;Iran should not target U.S. interests or personnel.&#8221;
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<blockquote class="twitter-tweet" data-width="500" data-dnt="true"><a href="https://t.co/aqh7QXYtiy">pic.twitter.com/aqh7QXYtiy</a>
&mdash; Rapid Response 47 (@RapidResponse47) <a href="https://twitter.com/RapidResponse47/status/1933324586214395966?ref_src=twsrc%5Etfw">June 13, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
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Asian markets opened lower on Friday, with Japan&#8217;s benchmark Nikkei 225 down 1.44%, trading at 37,625.30, with services, electronics, and export-oriented industries leading the decline. South Korea&#8217;s KOSPI Composite Index is following suit, down 0.97% in early-morning trade, at 2,891.73.
Crude oil prices are up 8% on Friday, trading at $73.36 a barrel, marking a steep ascent from its 52-week low of $58.4 in early May. 
Oil ETFs are once again on the ascent after hours, with the United States Oil Fund LP (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/USO#NYSE">USO</a>) up 1.68%, ProShares Ultra Bloomberg Crude Oil (ARCA: UCO) up 2.75%, and finally the SPDR S&amp;P Oil &amp; Gas Exploration &amp; Production ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/XOP#NYSE">XOP</a>) up 0.41%.
The U.S. Dollar Index (DXY) is up 0.21%, trading at 98.105 against a basket of foreign currencies, in a rather volatile trading session, as geopolitical concerns weigh.
Gold spot prices have surged 3.33%, trading at $3,435.68 per ounce, as investors pursue safe-haven assets amid rising geopolitical risks.
<figure class="wp-block-image size-large"><a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound"><img loading="lazy" decoding="async" width="1024" height="192" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/06/12215155/Screenshot-2025-06-13-at-7.21.28-AM-1024x192.png" alt="" class="wp-image-948339" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/06/12215155/Screenshot-2025-06-13-at-7.21.28-AM-1024x192.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/06/12215155/Screenshot-2025-06-13-at-7.21.28-AM-300x56.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/06/12215155/Screenshot-2025-06-13-at-7.21.28-AM-768x144.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/06/12215155/Screenshot-2025-06-13-at-7.21.28-AM.png 1176w" sizes="(max-width: 1024px) 100vw, 1024px" /></a></figure>
The ProShares Ultra Bloomberg Crude Oil ETF, one of the leading ETFs to track crude oil prices, has a momentum of 21.13. It has a favorable price trend in the short, medium, and long term, but how does it compare with other energy and crude oil ETFs? Click <a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound">here</a> to find out. 
Read More: 
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<li><a href="https://www.benzinga.com/markets/emerging-markets/25/06/45913847/the-dollar-is-crumbling-and-hedge-fund-analyst-says-a-new-global-trade-is-brewing">The Dollar Is Crumbling, And Hedge Fund Analyst Says A New Global Trade Is Brewing</a></li>
</ul>
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GENC

Middle East Tensions Rattle Markets: US Stock Futures Slide, Oil Jumps 8%, Gold Surges Above $3,400 After Israel Strikes Iran

Chip giant Nvidia Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVDA#NASDAQ">NVDA</a>) has revised its financial strategy after <a href="https://www.benzinga.com/government/regulations/25/04/44971572/nvidia-chip-ban-wont-stop-chinas-ai-momentum-say-analysts-blocking-h20-would-hand-market-to-huawei-amid-trump-era-export-crackdown">U.S. export controls</a> blocked AI chip sales to China, resulting in a multibillion-dollar revenue shortfall in the first quarter of 2025.
What Happened: Speaking <a href="https://edition.cnn.com/2025/06/12/tech/nvidia-ceo-china-us-ai-chip-exports">to</a> CNN in Paris on Thursday, Nvidia CEO Jensen Huang said the company will no longer include China in its revenue or profit forecasts due to ongoing U.S. export restrictions.
"I'm not counting on it, but if it happens, then it will be a great bonus," Huang said, referring to the possibility of loosened trade rules. "I've told all our investors and shareholders that, going forward, our forecasts will not include the China market."
Earlier this year, Nvidia was <a href="https://www.benzinga.com/25/05/45644145/nvidia-stock-is-bullish-ahead-of-q1-earnings-but-will-h20-chip-woes-dampen-the-party">forced to halt shipments</a> of its China-specific H20 AI chips after the U.S. government determined a special license was required.
That decision cost the company $2.5 billion in potential revenue in the first quarter. Although Nvidia <a href="https://www.benzinga.com/25/04/44830406/nvidia-to-take-55-billion-hit-over-china-chip-export-restrictions-but-top-analyst-dan-ives-says-hes-not-overly-concerned-all-part-of-the-high-game-of-poker">expected a $5.5 billion hit</a> from excess inventory, it ultimately recorded a $4.5 billion charge.
See Also:&nbsp;<a href="https://www.benzinga.com/25/04/44897214/nvidia-discusses-ai-powering-future-with-japan-amid-rising-energy-demands" target="_blank" rel="noreferrer noopener">Nvidia&#8217;s Jensen Huang Meets Japanese PM To Discuss AI&#8217;s Growing Energy Needs</a>
"The goals of the export controls are not being achieved," Huang told the publication. "Whatever those goals are that were being discussed initially, (they) are apparently not working. And so I think, with all export controls, the goals have to be well-articulated and tested over time."
Why It's Important: Speaking at the Viva Tech conference in Paris on Thursday, Huang also cautioned that continued U.S. restrictions on AI chip exports to China could allow Huawei Technologies to <a href="https://www.benzinga.com/markets/tech/25/06/45903869/nvidia-ceo-jensen-huang-says-huawei-has-got-china-covered-if-us-backs-off-despite-american-tech-being-generation-ahead">strengthen its position</a> within China.
On Monday, Kevin Hassett, who heads the U.S. National Economic Council, told CNBC that the Donald Trump administration could consider easing some <a href="https://www.benzinga.com/25/05/45157365/nvidia-ceo-jensen-huang-warns-us-lawmakers-that-export-bans-are-backfiring-fueling-huaweis-rise-in-global-ai-chip-race">export limits</a> on microchips deemed essential by China for its manufacturing needs, the report noted.
However, he said that the U.S. will continue to restrict access to "very, very high-end" Nvidia chips designed to support artificial intelligence systems.
Price Action: Nvidia shares have gained 4.84% year-to-date and are up 15.81% over the past 12 months. On Thursday, the stock climbed 1.52%, closing at $145, according to <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>.
Benzinga's Edge Stock Rankings show Nvidia maintaining strong upward momentum across short, medium and long-term periods. <a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound'">Further performance details are available here</a>.
<figure class="wp-block-image size-full"><a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound'"><img decoding="async" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/06/12220254/Screenshot-2025-06-13-at-7.30.48%E2%80%AFAM.png" alt="" class="wp-image-948344" /></a></figure>
Read More:
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<li><a href="https://benzinga.com/news/25/04/44735140/most-people-dont-have-the-balls-to-do-it-says-mark-cuban-praising-musk-for-going-all-in-with-his-own-money-f" target="_blank" rel="noreferrer noopener">‘Most People Don't Have The B&#x2A;&#x2A;ls To Do It,' Says Mark Cuban, Praising Musk For Going ‘All In' With His Own Money For His Startups</a></li>
</ul>
Disclaimer:&nbsp;This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.
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Tech

Media

NVDA

Nvidia Drops China From Guidance After $2.5 Billion Q1 Revenue Hit, CEO Jensen Huang Says He's 'Not Counting' On US Lifting Export Controls, 'But If It Happens, It Will Be A Great Bonus'

Leading cryptocurrencies nosedived Thursday as geopolitical tensions escalated following Israel&#8217;s military strikes on Iran.
<figure class="wp-block-table"> 
<table class="has-fixed-layout">
<thead>
<tr>
<th>Cryptocurrency</th>
<th>Gains +/-</th>
<th>Price (Recorded at 8:30 p.m. ET)</th>
</tr>
</thead>
<tbody>
<tr>
<td>Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>)</td>
<td>-4.51%</td>
<td>$103,584.63</td>
</tr>
<tr>
<td>Ethereum (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/eth/usd">ETH</a>) &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</td>
<td>-8.70%</td>
<td>$2,524.72</td>
</tr>
<tr>
<td>Dogecoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/doge/usd">DOGE</a>)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</td>
<td>-4.19%</td>
<td>$0.1879</td>
</tr>
</tbody>
</table>
</figure>
What Happened: Bitcoin crashed below $104,000 overnight, sending the larger cryptocurrency market into collapse.
Ethereum's decline was steeper, as it sank over 9% in the last 24 hours below $2,550. The second-largest cryptocurrency eroded the gains it made after the rally to $2,860. Dogecoin was also down over 4%.
The meltdown comes after Israel launched what it said was a "preemptive strike" against Iran, according to Defense Minister Israel Katz, <a href="https://edition.cnn.com/2025/06/12/middleeast/israel-iran-strikes-intl-hnk?Date=20250613&amp;Profile=CNN&amp;utm_content=1749774194&amp;utm_medium=social&amp;utm_source=twitter">reported</a> CNN. Katz said retaliatory strikes on Israel are expected.
Over $1 billion was liquidated from the cryptocurrency market in the last 24 hours, with an overwhelming $947 million in longs getting wiped out.
The derivative markets were spooked. Bitcoin&#8217;s Open Interest dropped 5.69%, while funds locked in Ethereum&#8217;s outstanding contracts declined by more than 13%.&nbsp;
Interestingly, Binance traders were buying Bitcoin's dip, as over 50% of them were positioned short, according to the Long/Short ratio.
The "Greed" sentiment plunged from 71 to 61 over the last 24 hours, according to the Crypto Fear &amp; Greed Index.
Top Gainers (24 Hours)
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<table class="has-fixed-layout">
<thead>
<tr>
<th>Cryptocurrency</th>
<th>Gains +/-</th>
<th>Price (Recorded at 8:30 p.m. ET)</th>
</tr>
</thead>
<tbody>
<tr>
<td>Kaia (KAIA)</td>
<td>+0.77%</td>
<td>$0.1721</td>
</tr>
<tr>
<td>Tether Gold (XAUt) &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</td>
<td>+0.66%</td>
<td>$3,385</td>
</tr>
<tr>
<td>Pax Gold (PAXG)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</td>
<td>+0.56%</td>
<td>$3,399.50 </td>
</tr>
</tbody>
</table>
</figure>
The global cryptocurrency market capitalization fell 1.38% in the last 24 hours to $3.39 trillion.
Stock futures bled overnight Thursday. The Dow Jones Industrial Average Futures tumbled 570 points, or 1.33%, as of 8:37 p.m. EDT.&nbsp; Futures tied to the S&amp;P 500 sank 1.43%, while Nasdaq 100 Futures lost 1.44%.
See More: <a href="https://www.benzinga.com/money/best-crypto-scanners">Best Cryptocurrency Scanners</a>
Analyst Notes: Widely followed cryptocurrency analyst Nebraskangooner warned that if Ethereum fails to hold a critical support level tied to a previous breakout around $2,500, it would likely drop lower.
&#8220;Zoomed out daily look with still plenty of time until tomorrows close but if it fails to hold the previous breakout candle base that would be a pretty nasty upthrust and likely signal lower levels to come,&#8221; the analyst said.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
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<blockquote class="twitter-tweet" data-width="500" data-dnt="true"><a href="https://twitter.com/search?q=%24ETH&amp;src=ctag&amp;ref_src=twsrc%5Etfw">$ETH</a> Zoomed out daily look with still plenty of time until tomorrows close but if it fails to hold the previous breakout candle base that would be a pretty nasty upthrust and likely signal lower levels to come. <a href="https://t.co/TNFSk0dUA6">pic.twitter.com/TNFSk0dUA6</a>
&mdash; Nebraskangooner (@Nebraskangooner) <a href="https://twitter.com/Nebraskangooner/status/1933330755461263619?ref_src=twsrc%5Etfw">June 13, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
Read Next:&nbsp;&nbsp;&nbsp;&nbsp;
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<li><a href="https://www.benzinga.com/crypto/cryptocurrency/25/06/45890085/stripe-acquires-crypto-wallet-infrastructure-startup-privy">Stripe Acquires Crypto Wallet Infrastructure Startup Privy</a></li>
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Photo Courtesy: alfernec on Shutterstock.com

Coverage of Bitcoin, Etherum, Ripple and all the latest digital currencies.

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$DOGE

$ETH

Bitcoin, Ethereum, Dogecoin Bleed After Israel Launches 'Premptive Strike' Against Iran: Analyst Foresees 'Lower Levels' For ETH If It Fails To Hold This Support

<a href="https://www.axios.com/2025/06/13/israel-strike-iran-trump-nuclear-talks" title="https://www.axios.com/2025/06/13/israel-strike-iran-trump-nuclear-talks">https://www.axios.com/2025/06/13/israel-strike-iran-trump-nuclear-talks</a>
<a href="https://www.axios.com/2025/06/13/israel-strike-iran-trump-nuclear-talks">https://www.axios.com/2025/06/13/israel-strike-iran-trump-nuclear-talks</a>

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iShares MSCI Israel Capped Investable Market Index Fund

'Israel conducts airstrike in Iran'- Axios

Confused over <a href="https://www.cnet.com/personal-finance/loans/the-end-of-save-expect-this-student-loan-plan-to-disappear-in-2025/https:/www.cnet.com/personal-finance/loans/the-end-of-save-expect-this-student-loan-plan-to-disappear-in-2025/">new rules</a> for student loans and repayments? Informed decisions made now could save thousands of dollars and lots of headaches trying to manage life's other financial challenges. Finance and policy expert Elaine Rubin worked for seven years at the U.S. Dept. of Education's Federal Student Aid office, making her extremely knowledgeable on this complex subject. Here is the <a href="https://www.cnet.com/personal-finance/loans/im-a-student-loan-expert-here-are-the-6-things-borrowers-should-do-now/">cheat sheet </a>of her three top tips to save money on your student loans.
Don't Miss:
<ul class="wp-block-list">
<li>Maker of the $60,000 foldable home has 3 factory buildings, 600+ houses built, and big plans to solve housing — <a href="https://www.benzinga.com/money/boxabl-scaling-fast-from-spacex-orders-to-600-homes-built-this-60k-foldable-home-may-be-the-future-of-housing">this is your last chance to become an investor for $0.80 per share.</a></li>
<li>‘Scrolling To UBI' — Deloitte's #1 fastest-growing software company allows users to earn money on their phones. <a href="https://www.benzinga.com/money/how-peter-thiel-turned-his-roth-ira-into-5-billion-and-why-accredited-investors-are-now-eyeing-this-smartphone-disruptor">You can invest today for just $0.30/share with a $1000 minimum.</a></li>
</ul>
<h2 class="wp-block-heading">Pull out the paperwork.</h2>
Find out what you've borrowed and how much you still owe. Copy or snap key figures for later reference if you don't want to slog through contracts and fine print. Include sections that show interest rates and how much they've been adding to your loan liability. Look at your repayment plans. Are you enrolled in the government's Saving on a Valuable Education Plan, also known as SAVE? If so, pay attention to <a href="https://www.cnet.com/personal-finance/loans/student-loan-borrowers-you-have-until-summer-to-prevent-your-wages-from-being-garnished/">garnishment rules</a> arising from legal challenges during the Biden administration.&nbsp;
Rubin says total indebtedness is a "question that most borrowers can't answer." She adds that folks behind in their payments often don't know it, adding to interest costs. "Many borrowers I&#8217;ve worked with are surprised to find they owe more than they initially borrowed when it&#8217;s time to start repayment, Rubin explained. "Because most loans, except subsidized ones, begin accruing interest from the moment they are disbursed."
Trending: Maximize saving for your retirement and cut down on taxes: <a href="https://www.benzinga.com/money/wideradvisor-retirement-planning">Schedule your free call with a financial advisor to start your financial journey – no cost, no obligation</a>.&nbsp;&nbsp;
<h2 class="wp-block-heading">Plan repayments and don't count on student loan forgiveness.</h2>
SAVE enrollees have been in limbo since last summer, caught in a court-ordered <a href="https://www.cnet.com/personal-finance/loans/save-student-loan-borrowers-likely-wont-make-payments-this-year-but-should-do-this-one-thing-now/">administrative forbearance</a>. That stopped interest rates, but the payment hold is scheduled to end no earlier than September, after government systems are updated. Check out the Department of Education&#8217;s <a href="https://studentaid.gov/loan-simulator/">Loan Simulator</a> for possible repayment options when the interest clock runs again. That site also has eligibility information for specific plans.
See Also: Invest where it hurts — and help millions heal:<a href="https://www.benzinga.com/money/a-cure-for-osteoarthritis-powered-by-everyday-investors-cytonics-is-looking-to-beat-big-pharma-and-disrupt-a-390-billion-market"> Invest in Cytonics and help disrupt a $390B Big Pharma stronghold</a>.
According to Rubin, borrowers can also restate income if they earn less now than at the time of the first loan forbearance in 2020. Lower income may reduce your student loan payment if you are enrolled in an income-driven repayment plan. Borrowers on that program may also qualify for student loan forgiveness. But they shouldn't count on relief because, as Rubin notes, "legal challenges continue to threaten SAVE and some of the other IDR repayment plans."&nbsp;&nbsp;
As a side note, teachers, nurses and other public service employees under the Department of Education's Public Service Loan Forgiveness program can cancel debt if they meet strict job length and repayment <a href="https://studentaid.gov/fsa-id/sign-in/landing">rules</a>.
<h2 class="wp-block-heading">Pay off as much interest as possible when you're still in school.&nbsp;</h2>
Not everyone has the resources to pay for college, and a college loan, at the same time. But student loans generally don't start the repayment clock until six months after graduation, or after failing to meet enrollment guidelines. So, Rubin says it helps if the borrower can "pay off any interest that accrues while you&#8217;re still in school. Even small contributions can help reduce the overall cost of your loans in the long run."
Read Next:
<ul class="wp-block-list">
<li>Many are using retirement income calculators to check if they&#8217;re on pace —<a href="https://www.benzinga.com/money/how-do-i-calculate-my-retirement-income-adv"> here&#8217;s a breakdown on what&#8217;s behind this formula.</a></li>
<li>Deloitte's fastest-growing software company partners with Amazon, Walmart &amp; Target – <a href="https://www.benzinga.com/money/how-peter-thiel-turned-his-roth-ira-into-5-billion-and-why-accredited-investors-are-now-eyeing-this-smartphone-disruptor">Many are rushing to grab 4,000 of its pre-IPO shares for just $0.30/share!</a></li>
</ul>
Image: Shutterstock

Personal Finance

Don't Wait – These 3 Steps Could Save you a Ton on Your Student Loans

ONCO

Trading Halt: Halted at 7:50:00 p.m. ET - Trading Halt: Halt News Pending

Applied Industrial Techs (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AIT#NYSE">AIT</a>) has outperformed the market over the past 10 years by 7.2% on an annualized basis producing an average annual return of 18.31%. Currently, Applied Industrial Techs has a market capitalization of $8.84 billion. 
Buying $100 In AIT: If an investor had bought $100 of AIT stock 10 years ago, it would be worth $538.95 today based on a price of $230.24 for AIT at the time of writing.
<h3>Applied Industrial Techs's Performance Over Last 10 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1749771911_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

$100 Invested In This Stock 10 Years Ago Would Be Worth This Much Today

MercadoLibre (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MELI#NASDAQ">MELI</a>) has outperformed the market over the past 15 years by 15.97% on an annualized basis producing an average annual return of 27.88%. Currently, MercadoLibre has a market capitalization of $119.44 billion. 
Buying $1000 In MELI: If an investor had bought $1000 of MELI stock 15 years ago, it would be worth $38,992.92 today based on a price of $2356.00 for MELI at the time of writing.
<h3>MercadoLibre's Performance Over Last 15 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1749771013_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

MELI

Here's How Much $1000 Invested In MercadoLibre 15 Years Ago Would Be Worth Today

McKesson (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MCK#NYSE">MCK</a>) has outperformed the market over the past 20 years by 6.76% on an annualized basis producing an average annual return of 15.11%. Currently, McKesson has a market capitalization of $91.59 billion. 
Buying $100 In MCK: If an investor had bought $100 of MCK stock 20 years ago, it would be worth $1,682.32 today based on a price of $730.80 for MCK at the time of writing.
<h3>McKesson's Performance Over Last 20 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1749770112_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

Here's How Much $100 Invested In McKesson 20 Years Ago Would Be Worth Today

The world's richest billionaire has taken a hit to his wealth in 2025. Even after a year-to-date decline for Tesla Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TSLA#NASDAQ">TSLA</a>) stock, Elon Musk is still significantly ahead of who is in second place and worth more than several of his automotive rivals combined.
What Happened: Tesla CEO Elon Musk is the world's richest person and gets the majority of his net worth from ownership stakes in the electric vehicle company, SpaceX, xAI and other ventures.
Musk currently ranks first as the world's richest with a wealth of $369 billion according to <a href="https://www.bloomberg.com/billionaires/?sref=TBDibEcD">Bloomberg</a>.
This is significantly ahead of the billionaire in second place, Mark Zuckerberg, who is worth an estimated $245 billion.
What's also interesting is that if you look at Musk's wealth, it&#8217;s worth more than several of the largest automotive companies combined.
Take this list, for example:
<ul class="wp-block-list">
<li>Stellantis NV (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/STLA#NYSE">STLA</a>): $29.7 billion</li>
<li>Ford Motor Company (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/F#NYSE">F</a>): $41.9 billion</li>
<li>General Motors Company (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GM#NYSE">GM</a>): $47.4 billion</li>
<li>Toyota Motor Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TM#NYSE">TM</a>): $238.2 billion</li>
</ul>
Add it up and it's a value of $357.2 billion. That means Musk is worth more than these four automotive companies combined, with $11.8 billion left over.
You may not be a billionaire like Elon Musk, but you can uncover hidden gems in the stock market using our proprietary data and pattern recognition — <a href="https://www.benzinga.com/general/entertainment/24/10/41187322/benzingas-stock-whisper-index-5-stocks-investors-secretly-monitor-but-dont-talk-about-yet">check out five stocks flying under the radar that </a><a href="https://www.benzinga.com/trading-ideas/long-ideas/25/06/45827517/benzingas-stock-whisper-index-5-stocks-investors-secretly-monitor-but-dont-talk-about-yet-68">deserve </a><a href="https://www.benzinga.com/general/entertainment/24/10/41187322/benzingas-stock-whisper-index-5-stocks-investors-secretly-monitor-but-dont-talk-about-yet">your attention.</a>
Why It's Important: Musk and Tesla have dominated the electric vehicle market in the U.S. and globally.
Tesla is worth over $1 trillion, even with recent struggles with delivery figures and demand.
A recent public feud between Musk and President Donald Trump sent shares of Tesla down significantly, marking the company&#8217;s biggest one-day market capitalization <a href="https://www.benzinga.com/markets/25/06/45827390/musk-vs-trump-tesla-suffers-record-152b-one-day-crash-as-ceo-warns-tariffs-will-cause-a-recession-up">loss of $152 billion.</a>
That drop also<a href="https://www.benzinga.com/news/movers-shakers/25/06/45807280/elon-musk-bleeds-34-billion-as-tesla-shares-tank-14-amid-spat-with-trump-how-the-billionaires-fortune-has-fared-so-far-in-2025"> sent the wealth </a>of Musk from $368 billion on June 4 to $335 billion on June 5.
Tesla stock and Musk's wealth have rebounded from that feud-related sell-off.
Tesla stock remains down 15.9% year-to-date.
Musk's wealth has taken a hit in 2025 with a $63.5 billion drop in his net worth over the year. This comes with Tesla stock falling, while other ventures of his such as Neuralink, xAI and SpaceX are seeing higher valuations.
Musk became the first person to have a net worth of more than $400 billion in late 2024 and he could be headed back to that figure if Tesla stock can rally on recent robotaxi news and turn positive on the year.
Read Next: 
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<li><a href="https://www.benzinga.com/news/politics/25/06/45845525/exclusive-should-musk-be-fired-from-tesla-after-trump-feud-45-say-this-in-new-poll">EXCLUSIVE: Should Musk Be Fired From Tesla After Trump Feud? 45% Say This In New Poll</a></li>
</ul>
Photo: Shutterstock

Entertainment

Management

STLA

TSLA

Elon Musk Net Worth Down $64 Billion In 2025 — But Tesla CEO Still Richer Than Value Of Ford, General Motors, Stellantis, Toyota Combined

Halozyme Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HALO#NASDAQ">HALO</a>) has outperformed the market over the past 15 years by 2.54% on an annualized basis producing an average annual return of 14.44%. Currently, Halozyme Therapeutics has a market capitalization of $6.72 billion. 
Buying $100 In HALO: If an investor had bought $100 of HALO stock 15 years ago, it would be worth $764.94 today based on a price of $54.54 for HALO at the time of writing.
<h3>Halozyme Therapeutics's Performance Over Last 15 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1749768313_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

HALO

Here's How Much $100 Invested In Halozyme Therapeutics 15 Years Ago Would Be Worth Today

An 80-year-old woman packed and ready to move says she's trapped in her apartment because a nonprofit is still holding onto her Social Security benefits — even after the program that once supported her abruptly shut down and gave her just 10 days to leave.
According to a report by <a href="https://youtu.be/-VPe0qo4Zco?si=QXw0fXzvELgktQTJ">WHEC-TV</a> in Rochester, New York, Georgia Johnson is one of many elderly and disabled residents evicted from Hudson Ridge and Danforth Towers in Rochester following the sudden closure of the Enriched Housing Program last month. The program, run by Family Service of Rochester, was supposed to help residents live independently by using their government benefits to pay rent and provide support services.
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Instead, residents say they were blindsided.
"This country is supposed to be the land of the free and the home of the brave," Johnson said. "But in other countries, they take care of their elders."
Johnson has end-stage congestive heart failure and kidney failure. Though she's mentally sharp, she's physically frail. Her belongings are packed in bins and boxes — but she can't move. She says Family Service of Rochester still controls her money and hasn't returned it.
"How can they be so heartless to take people's money when they have to live?" Johnson asked.
She said the organization promised to refund her May <a href="https://www.benzinga.com/personal-finance/25/05/45665342/social-security-is-the-main-source-of-income-for-retirees-in-these-10-states-is-your-state-on-the-list">Social Security check</a> and told her it would be returned by May 20, but the money never came. Her daughter, Jannine Johnson, helped her file paperwork with the Social Security office to remove Family Service as her representative payee.
"That money was supposed to be put in mommy's account on [June 3]," said Jannine.
Trending: Maximize saving for your retirement and cut down on taxes: <a href="https://www.benzinga.com/money/wideradvisor-retirement-planning">Schedule your free call with a financial advisor to start your financial journey – no cost, no obligation</a>.&nbsp;
But it didn't happen, Jannine said. The Social Security Administration mistakenly sent the June check back to Family Service. Johnson was then instructed to get the nonprofit to issue her a check.
She's tried. She's still waiting.
Family Service of Rochester told WHEC in a <a href="https://www.whec.com/top-news/consumer-alert-nonprofit-still-has-seniors-social-security-benefits-after-ending-program/">statement</a> that it is following instructions from the local Social Security office and will continue to act as payee until officially replaced,
Johnson's situation is made worse by the <a href="https://www.benzinga.com/personal-finance/25/05/45602625/78-year-old-florida-woman-on-social-security-has-been-living-in-her-car-for-months-because-she-cant-afford-rent-i-eat-one-meal-a-day-for-2-02">type of housing now being offered</a>.
"Want to hear the shocker?" she said. "They told me — you see all this stuff here? — they told me I was going to be in one room with a partner."
"That wasn't even a downsize. That was a no-size," she added.
Her daughter has found an assisted living facility that could work — if they can access the funds. Until then, Johnson remains stuck in limbo.
The state Department of Health told WHEC that the quality of care provided by the nonprofit was so poor it endangered residents' health and safety. Meanwhile, the Rochester Housing Authority claims Family Service is $400,000 behind in rent payments.
The legal scrutiny is now intensifying.
See Also: Invest where it hurts — and help millions heal:<a href="https://www.benzinga.com/money/a-cure-for-osteoarthritis-powered-by-everyday-investors-cytonics-is-looking-to-beat-big-pharma-and-disrupt-a-390-billion-market"> Invest in Cytonics and help disrupt a $390B Big Pharma stronghold</a>.
The Monroe County District Attorney and the New York State Attorney General's Office both confirm they are investigating the situation. The U.S. Attorney's Office has not confirmed whether it has opened a case, according to the report.&nbsp;
WHEC reported that Family Service said it is working with Social Security officials to get Johnson's money returned.
Her story has sparked outrage online, where commenters have called the situation "shameful," "cruel," and "the kind of thing that shouldn't happen in America." Some expressed disbelief that a nonprofit could still act as a payee after shutting down services. Others shared their own experiences trying to help elderly parents reclaim benefits from similar arrangements.
A few offered non-legal suggestions: visiting the <a href="https://www.ssa.gov/agency/contact/phone.html">local SSA office in person</a>, escalating to the fraud department, and involving elected officials who can expedite SSA actions. One user wrote, "My mom got her money back only after we filed a congressional inquiry." Another added, "Keep calling. The squeaky wheel gets the oil."
While Johnson and her daughter continue pushing through the system, the money intended to support her still sits out of reach — held by a service that no longer exists.
Read Next:
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<li>Many are using retirement income calculators to check if they&#8217;re on pace —<a href="https://www.benzinga.com/money/how-do-i-calculate-my-retirement-income-adv"> here&#8217;s a breakdown on what&#8217;s behind this formula.</a></li>
<li>‘Scrolling To UBI' — Deloitte's #1 fastest-growing software company allows users to earn money on their phones. <a href="https://www.benzinga.com/money/how-peter-thiel-turned-his-roth-ira-into-5-billion-and-why-accredited-investors-are-now-eyeing-this-smartphone-disruptor">You can invest today for just $0.30/share with a $1000 minimum.</a></li>
</ul>
Image: Shutterstock

'That Wasn't Even a Downsize — That Was a No-Size': 80-Year-Old Says Nonprofit Housing Agency Shut Down But Is Still Getting Her Social Security Check

KKR (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/KKR#NYSE">KKR</a>) has outperformed the market over the past 15 years by 6.29% on an annualized basis producing an average annual return of 18.2%. Currently, KKR has a market capitalization of $111.54 billion. 
Buying $1000 In KKR: If an investor had bought $1000 of KKR stock 15 years ago, it would be worth $12,278.43 today based on a price of $125.24 for KKR at the time of writing.
<h3>KKR's Performance Over Last 15 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1749767413_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

$1000 Invested In This Stock 15 Years Ago Would Be Worth This Much Today

Retailer Walmart Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/WMT#NYSE">WMT</a>) <a href="https://www.benzinga.com/markets/25/05/45536218/walmart-responds-to-trumps-eat-the-tariff-remark-worked-to-keep-our-prices-as-low-as-possible-and-we-wont-stop">has been battling</a> with the Donald Trump administration over tariffs and may have a new fight on its hands with Trump fans thanks to an heiress of the company's founding family.
What Happened: Walmart and the Trump administration have been going back and forth on tariffs and whether the retailer can publicly say it <a href="https://www.benzinga.com/news/retail-sales/25/06/45829026/walmart-shoppers-see-sharp-price-hikes-as-tariffs-hit-shelves">is passing costs </a>onto consumers.
An additional issue, which could possibly mean the retailer finds itself with fewer customers, is if it battles too hard with Trump fans due to Christy Walton.
Walton is the widow of John T. Walton, son of Walmart founder Sam Walton. The Walmart heiress funded a full-page ad for the "No Kings" movement placed in the New York Times, the New York Post <a href="https://nypost.com/2025/06/11/business/walmart-heiress-christy-waltons-anti-trump-ad-fuels-maga-led-call-for-boycott-of-retailer/">reported</a>.
The ad calls for a nationwide protest against Trump and asks Americans and other citizens to "mobilize" on Saturday, which is Trump's birthday and the day of a large military parade in the nation's capital.
Walton's funded ad also calls on Americans to "reject authoritarianism."
According to the report, the "No Kings" movement is planning around 1,500 nationwide protests on Saturday. The report notes that the movement is not holding a protest in Washington, D.C. on Saturday on purpose.
"The honor, dignity, and integrity of our country are not for sale," the ad reads, alongside a QR code that shows the map of protest locations.
A Christy Walton spokesperson said the ad does not encourage violent protests, but rather to "engage peacefully and civically."
"Christy has provided no funding to organizations or individuals involved in the demonstrations in Los Angeles or other cities, nor has she provided any funding to those organizing the upcoming events," the spokesperson said.
The spokesperson said Walton believes Americans have the right to protest, but not the right to violence.
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Why It's Important: Walton is not involved in Walmart's operations, but her actions could end up hurting the future growth and revenue of the company her former husband's family founded. She maintains a 1.9% stake in the company.
Walton is worth $18.6 billion according to <a href="https://www.bloomberg.com/billionaires/?sref=TBDibEcD">Bloomberg</a>, ranking 117th among the world's billionaires. This trails other Walton figures like her son Lukas Walton, who is the 39th richest person worth $41.1 billion, and her husband's siblings Jim, Rob and Alice Walton, who rank 13th, 14th and 15th worth $119 billion, $117 billion and $116 billion, respectively.
The White House responded to the ad and brushed aside Walton's criticism.
"Great, a left-wing billionaire feels like burning some of her inheritance for a PR stunt," White House spokesman Kush Desai told The Post.
Desai said the ad would not change the fact that more than 77 million Americans voted for Trump and his "America First trade policies."
Some Trump allies indirectly and directly called for a boycott of Walmart.
White House special adviser Kari Lake shared the ad on X and asked her followers, "Do you shop at Walmart?"
Rep. Anna Paulina Luna (R-Fla.) posted on X that Walton is funding ads for "No Kings Day," while naming her as a Walmart heiress.
"Looks like the Walmart dynasty is big mad about China tariffs," Luna said.
Trump supporter Roger Stone encouraged people to boycott Walmart.
"The Walmart heiress subsidizes insurrection. Next up, peaceful protests outside all of their stores to encourage people not to shop there. Essentially what left-wing stooges did to Tesla," Stone said.
Walmart has tried to distance itself from Walton.
"The advertisement from Christy Walton [is] in no way connected to or endorsed by Walmart," Walmart spokesperson Joe Pennington said.
Pennington said Walton "has no active role in company decisions."
This could end up being an unfortunate situation for Walmart and shareholders as a major boycott effort by Trump fans could impact sales. Walmart locations are often times found in rural locations and small cities that have leaned towards voting for Trump in recent elections.
WMT Price Action: Walmart stock closed down 1.01% to $94.83 on Thursday versus a 52-week trading range of $65.95 to $105.30. Walmart stock is up 5.4% year-to-date in 2025.
Read Next: 
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<li><a href="https://www.benzinga.com/news/management/25/05/45473067/walmart-prices-will-rise-within-weeks-as-trump-tariffs-drive-up-costs-will-other-retailers-follow-suit">Walmart Prices Will Rise Within Weeks As Trump Tariffs Drive Up Costs: Will Other Retailers Follow Suit?</a></li>
</ul>
Photo: Shutterstock

Walmart Heiress Takes On Trump With 'No Kings' Ad: White House Calls It 'Burning Some Of Her Inheritance For A PR Stunt'

ServiceNow (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/NOW#NYSE">NOW</a>) has outperformed the market over the past 5 years by 6.34% on an annualized basis producing an average annual return of 20.38%. Currently, ServiceNow has a market capitalization of $208.81 billion. 
Buying $100 In NOW: If an investor had bought $100 of NOW stock 5 years ago, it would be worth $256.65 today based on a price of $1008.00 for NOW at the time of writing.
<h3>ServiceNow's Performance Over Last 5 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1749766512_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

Here's How Much $100 Invested In ServiceNow 5 Years Ago Would Be Worth Today

CLDX

Celldex Therapeutics Announces 76-Week Results From Barzolvolimab Phase 2 Study In Chronic Spontaneous Urticaria At EAACI Congress 2025; Up To 41% Of Patients Reporting A Complete Response At 76 Weeks And 48% Of Patients Reporting That Their Disease No Longer Impacts Their Quality Of Life; Enrollment to Phase 3 CSU Trials Ongoing

BPMC

Blueprint Medicines Reveals Data Reinforcing Sustained Clinical Efficacy And Well-Tolerated Safety Profile of Long-Term AYVAKIT/AYVAKYT Treatment At 2025 EHA And EAACI Congresses

WIIM

ADBE

ADBE stock has given up its prior gain. Adobe shares were trading higher after the company reported better-than-expected Q2 financial results and raised its FY25 guidance.

<a href="https://www.bloomberg.com/news/articles/2025-06-12/nrg-expects-to-line-up-new-us-data-center-deals-this-quarter?embedded-checkout=true">https://www.bloomberg.com/news/articles/2025-06-12/nrg-expects-to-line-up-new-us-data-center-deals-this-quarter?embedded-checkout=true</a>

'NRG Expects to Line Up New US Data Center Deals This Quarter'- Bloomberg

In the current market session, ServiceNow Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/NOW#NYSE">NOW</a>) share price is at $1008.00, after a 0.37% increase. Moreover, over the past month, the stock decreased by 2.69%, but in the past year, went up by 38.26%. Shareholders might be interested in knowing whether the stock is overvalued, even if the company is performing up to par in the current session. 

<img src="https://www.benzinga.com/files/images/story/2025/1749765619_0.png" alt="Past Year Chart" />

<h3>A Look at ServiceNow P/E Relative to Its Competitors</h3>
The P/E ratio measures the current share price to the company's EPS. It is used by long-term investors to analyze the company's current performance against it's past earnings, historical data and aggregate market data for the industry or the indices, such as S&amp;P 500. A higher P/E indicates that investors expect the company to perform better in the future, and the stock is probably overvalued, but not necessarily. It also could indicate that investors are willing to pay a higher share price currently, because they expect the company to perform better in the upcoming quarters. This leads investors to also remain optimistic about rising dividends in the future. 
ServiceNow has a better P/E ratio of 136.27 than the aggregate P/E ratio of 92.8 of the Software industry. Ideally, one might believe that ServiceNow Inc. might perform better in the future than it's industry group, but it's probable that the stock is overvalued. 

<img src="https://www.benzinga.com/files/images/story/2025/1749765619_1.png" alt="Guage" />

In conclusion, the price-to-earnings ratio is a useful metric for analyzing a company's market performance, but it has its limitations. While a lower P/E can indicate that a company is undervalued, it can also suggest that shareholders do not expect future growth. Additionally, the P/E ratio should not be used in isolation, as other factors such as industry trends and business cycles can also impact a company's stock price. Therefore, investors should use the P/E ratio in conjunction with other financial metrics and qualitative analysis to make informed investment decisions.

Intraday Update

Price Over Earnings Overview: ServiceNow

Earnings

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Lyra Therapeutics Reports Second Quarter 2024 Financial Results and Provides Corporate Update

Lyra Therapeutics to Present Study Results for LYR-210 and LYR-220 in Two Presentations at the ARS and AAO-HNS Annual Meetings

Health Care

Lyra Therapeutics Fully Enrolls Pivotal Phase 3 ENLIGHTEN 2 Trial of LYR-210 for the Treatment of Chronic Rhinosinusitis

Lyra Therapeutics Reports Third Quarter 2024 Financial Results and Provides Corporate Update

Incendia Therapeutics Appoints Bradford Smith as Chief Financial Officer

Lyra Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update

Lyra Therapeutics Reports First Quarter 2025 Financial Results and Provides Corporate Update

Lyra Therapeutics to Present 52-week Extension Stage Results for ENLIGHTEN 1 Phase 3 Study for LYR-210 for the Treatment of Chronic Rhinosinusitis at COSM 2025

Analyst Ratings

Lyra Therapeutics Reports Positive Results from the ENLIGHTEN 2 Phase 3 Trial of LYR-210 Achieving Statistically Significant Results for Primary and Key Secondary Endpoints in the Treatment of Chronic Rhinosinusitis (CRS)

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