Bulls vs Bears
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Market sentiment signals for Spero Therapeutics (SPRO): analyst consensus, short interest, options flow and insider activity.
Analyst Consensus
In-Line
5 analysts
Options Flow (P/C)
5.33
More puts — Bearish
Avg Consensus PT
$6
+455.9%
Highest Price Target
$6
+488.2%
Lowest Price Target
$5
+390.2%
Short Interest
1.7%
Rising — Bearish
Insider Activity (30d)
—
Short Interest — % of Float
| Date | Firm | Analyst & Accuracy | Upside / Downside | PT Change | Action | Rating |
|---|---|---|---|---|---|---|
| Oct 28, 2026 | Cantor Fitzgerald | Kristen Kluska— | +488.2% | $6 | Initiate | Overweight |
| Sep 14, 2026 | HC Wainwright & Co. | Raghuram Selvaraju— | +488.2% | $5 → $6 | Maintained | Buy |