Ultime notizie per Amarin Corp (NASDAQ:AMRN) Azioni

Amarin Corp

Amarin Corp PLC is a biopharmaceutical company. It is focused on the commercialization and development of therapeutics to improve cardiovascular, or CV, health and reduce CV risk. Its commercialized product includes Vascepa.

Amarin Corporation plc - American Depositary Shares, each representing one Ordinary Share

Amarin Corp PLC

AMARIN ADR REP 1 ORD

Amarin Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMRN#NASDAQ">AMRN</a>) reported quarterly losses of $(0.06) per share which missed the analyst consensus estimate of $(0.05) by 20 percent. The company reported quarterly sales of $42.300 million which missed the analyst consensus estimate of $44.510 million by 4.96 percent. This is a 35.96 percent decrease over sales of $66.056 million the same period last year.

Earnings

Earnings Misses

News

AMRN

Amarin Corp Q3 2024 GAAP EPS $(0.06) Misses $(0.05) Estimate, Sales $42.300M Miss $44.510M Estimate

Amarin Corporation plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMRN#NASDAQ">AMRN</a>) today announced new supported and/or funded subgroup data from the landmark REDUCE-IT&#xAE; cardiovascular outcomes trial with VASCEPA&#xAE;/VAZKEPA&#xAE; (icosapent ethyl), as well as abstracts showcasing the mechanistic activity of eicosapentaenoic&nbsp;acid (EPA) that will be presented at the European Society of Cardiology (ESC) Congress in London, United Kingdom, August 30 – September 2, 2024.
The accepted abstracts include a REDUCE-IT subgroup analysis to assess if baseline small dense low density lipoprotein cholesterol (sdLDL-C) modifies the effect of icosapent ethyl (IPE) on cardiovascular events. A second abstract examines the association of triglycerides with cardiovascular events in patients with initial or recurrent acute coronary syndrome (ACS). A third abstract estimates the number of ACS patients eligible for IPE in Spanish hospitals, and finally, a fourth abstract measures the effects of EPA on oxidation of Lp(a) under experimental conditions of high glucose.

Biotech

General

Amarin Shares Latest Research Highlighting VASCEPA/VAZKEPA REDUCE-IT Subgroup Data And New Mechanistic Insights Into Eicosapentaenoic Acid To Be Presented At ESC Congress 2024

WIIM

Amarin shares are trading lower. The company reported Q2 financial results.

Guidance

Amarin Reiterates For FY24 It Believes That Current Cash And Investments And Other Assets Are Adequate To Support Continued Operations

Amarin Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMRN#NASDAQ">AMRN</a>) reported quarterly earnings of $0.01 per share which beat the analyst consensus estimate of $(0.04) by 125 percent. The company reported quarterly sales of $67.500 million which beat the analyst consensus estimate of $51.019 million by 32.30 percent. This is a 15.80 percent decrease over sales of $80.167 million the same period last year.

Earnings Beats

Amarin Corp Q2 2024 Adj. EPS $0.01 Beats $(0.04) Estimate, Sales $67.500M Beat $51.019M Estimate

Under the terms of the PLA, Vascepa will be reimbursed as a Special Authority product by Alberta Health for the secondary prevention of cardiovascular events (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, coronary revascularization or hospitalization for unstable angina) in statin-treated patients with established cardiovascular disease and elevated triglycerides.

Health Care

HLS Therapeutics Has Entered Into A Product Listing Agreement With The Province Of Alberta, For The Listing And Public Reimbursement Of Amarin's Vascepa (Icosapent Ethyl), Effective August 1, 2024

Amarin shares are trading higher after the company received national reimbursement for VAZKEPA in Portugal.

Portuguese Ministry Of Health Approves VAZKEPA For National Reimbursement To Reduce Cardiovascular Risk In High-Risk Patients; Eighth National Reimbursement In Europe; Amarin To Begin Commercialization In Portugal On August 1, 2024

Amarin's China Partner EddingPharm Receives Regulatory Approval From NMPA For VASCEPA In Mainland China For Cardiovascular Risk Reduction

Cantor Fitzgerald analyst Louise Chen reiterates Amarin Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMRN#NASDAQ">AMRN</a>) with a Overweight.

Reiteration

Analyst Ratings

Cantor Fitzgerald Reiterates Overweight on Amarin Corp

Shares of Core &amp; Main Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CNM#NYSE">CNM</a>) fell sharply during Tuesday's session after the company reported <a href="https://www.benzinga.com/quote/CNM/earnings">mixed first-quarter financial results.</a>
Core &amp; Main posted quarterly earnings of 49 cents per share, missing market expectations of 52 cents per share. The company's quarterly sales came in at $1.74 billion versus estimates of $1.72 billion, according to data from <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>.
Core &amp; Main shares dipped 11.4% to $49.77 on Tuesday.
Here are some other stocks moving in today&#8217;s mid-day session.
<h3 class="wp-block-heading">Gainers</h3>
<ul>
<li>MicroAlgo Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MLGO#NASDAQ">MLGO</a>) shares jumped 284% to 5.99 after the company announced that it will jointly establish a micro-consciousness quantum research center with WiMi.</li>
<li>Sobr Safe Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SOBR#NASDAQ">SOBR</a>) surged 112% to $0.56 after the company announced SOBRsure device purchases from two new customers.</li>
<li>Annexon, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ANNX#NASDAQ">ANNX</a>) climbed 40% to $6.44 after the company&#8217;s Phase 3 trial of ANX005 met its primary endpoint.</li>
<li>WiMi Hologram Cloud Inc &#8211; ADR (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/WIMI#NASDAQ">WIMI</a>) shares gained 37.3% to $1.18 after the company announced that the company and MicroAlgo will jointly establish a micro-consciousness quantum research center.</li>
<li>Core Scientific Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CORZ#NASDAQ">CORZ</a>) shares rose 29% to $6.28. Core Scientific announced the signing of a series of 12-year contracts with CoreWeave, the AI Hyperscaler.</li>
<li>Oblong Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/OBLG#NASDAQ">OBLG</a>) gained 25% to $0.32 after the company announced that it signed a non-binding letter of intent to acquire Dwellwell Analytics.</li>
<li>Captivision Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CAPT#NASDAQ">CAPT</a>) shares climbed 22.7% to $4.16 after dipping 28% on Monday.</li>
<li>Marin Software Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MRIN#NASDAQ">MRIN</a>) gained 21.2% to $2.97. Marin Software announced expanded Amazon integration to unlock channel for all advertisers.</li>
<li>Moving Image Technologies Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MITQ#NYSE">MITQ</a>) gained 20.2% to $0.67.</li>
<li>Alset Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AEI#NASDAQ">AEI</a>) shares climbed 19.4% to $1.23</li>
<li>CareCloud Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CCLD#NASDAQ">CCLD</a>) shares gained 18.2% to $3.54.</li>
<li>Saia Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SAIA#NASDAQ">SAIA</a>) shares climbed 12.3% to $452.00 after the company reported an 18% increase in LTL shipments per workday in April.</li>
<li>Terawulf Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/WULF#NASDAQ">WULF</a>) gained 12% to $2.30 after the company issued May 2024 production and operations update.</li>
<li>SINTX Technologies Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SINT#NASDAQ">SINT</a>) gained 11.8% to $7.28.</li>
<li>Zai Lab Ltd – ADR (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ZLAB#NASDAQ">ZLAB</a>) shares rose 9.9% to $19.78.</li>
<li>Hillevax Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HLVX#NASDAQ">HLVX</a>) gained 9.7% to $13.60.</li>
<li>Agenus Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AGEN#NASDAQ">AGEN</a>) shares rose 9.3% to $18.55.</li>
<li>SkyWest Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SKYW#NASDAQ">SKYW</a>) gained 5.6% to $83.87.</li>
<li>Forward Air Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FWRD#NASDAQ">FWRD</a>) gained 3.9% to $17.88.</li>
</ul>
<h3 class="wp-block-heading">Losers</h3>
<ul>
<li>ENDRA Life Sciences Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NDRA#NASDAQ">NDRA</a>) shares fell 66.4% to $0.073 after the company announced pricing of $8.0 million public offering.</li>
<li>Avalon Globocare Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ALBT#NASDAQ">ALBT</a>) shares fell 30.9% to $0.85 after surging 317% on Monday.</li>
<li>Equillium Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/EQ#NASDAQ">EQ</a>) fell 25.2% to $1.10 after the company announced topline data from its Phase 2 study of EQ101 in alopecia areata.</li>
<li>JIADE Ltd (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/JDZG#NASDAQ">JDZG</a>) fell 21.3% to $9.81.</li>
<li>Designer Brands Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/DBI#NYSE">DBI</a>) shares fell 20.5% to $8.79 following first-quarter earnings.</li>
<li>MingZhu Logistics Holdings Ltd (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/YGMZ#NASDAQ">YGMZ</a>) shares fell 17.5% to $0.38. MingZhu Logistics Holdings shares jumped 32% on Monday after the company announced an agreement to acquire Oxylus Global.</li>
<li>Humacyte Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HUMA#NASDAQ">HUMA</a>) shares declined 17.1% to $6.11.</li>
<li>NewGenIvf Group Ltd (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NIVF#NASDAQ">NIVF</a>) shares fell 16.8% to $1.15. On Monday, NewGenIvf signed a non-binding $617.34 million deal for potential reverse merger with pharma company COVIRIX.</li>
<li>GCT Semiconductor Holding Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GCTS#NYSE">GCTS</a>) shares declined 14.6% to $3.92</li>
<li>CalAmp Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CAMP#NASDAQ">CAMP</a>) shares declined 14% to $0.87. CalAmp recently entered into a restructuring support agreement to take the company private and has voluntarily initiated proceedings under Chapter 11 of the United States Bankruptcy Code.</li>
<li>Nuscale Power Corp (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SMR#NYSE">SMR</a>) shares fell 12.2% to $6.70.</li>
<li>Amarin Corporation plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMRN#NASDAQ">AMRN</a>) shares declined 12% to $0.75 after the company announced that it appointed Aaron Berg as President and CEO.</li>
<li>Cibus Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CBUS#NASDAQ">CBUS</a>) shares declined 11.4% to $11.76.</li>
<li>Ivanhoe Electric Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/IE#NYSE">IE</a>) shares fell 10% to $9.73.</li>
<li>Bath &amp; Body Works Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BBWI#NYSE">BBWI</a>) fell 10.5% to $46.39 after the company reported first-quarter earnings.</li>
<li>ICICI Bank Ltd (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/IBN#NYSE">IBN</a>) shares declined 10.4% to $25.38 as Indian stocks moved lower amid early results from India&#8217;s general election.</li>
<li>Microbot Medical Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MBOT#NASDAQ">MBOT</a>) shares fell 9.4% to $1.25 after jumping 38% on Monday.</li>
<li>Bark Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BARK#NYSE">BARK</a>) shares declined 9.3% to $1.27 after the company reported downbeat financial results for its fourth quarter and issued FY25 revenue guidance below estimates.</li>
<li>HDFC Bank Ltd (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/HDB#NYSE">HDB</a>) declined 9.2% to $55.62 as Indian stocks moved lower amid early results from India&#8217;s general election.</li>
<li>Hywin Holdings Ltd &#8211; ADR (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HYW#NASDAQ">HYW</a>) shares fell 9% to $0.61 after jumping 91% on Monday.</li>
<li>Axos Financial Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AX#NYSE">AX</a>) shares fell 8.9% to $47.79 after Short seller Hindenburg Research issued a short report on the stock.</li>
<li>Modine Manufacturing Co (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MOD#NYSE">MOD</a>) shares fell 8.7% to $91.14.</li>
<li>Arch Resources Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ARCH#NYSE">ARCH</a>) shares declined 8.4% to $164.81.</li>
<li>Dave Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DAVE#NASDAQ">DAVE</a>) fell 7.5% to $35.05. Dave announced an extension of its official partnership with the Drew League, Los Angeles&#8217; premiere Pro-Am basketball league.</li>
<li>GameStop Corp (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GME#NYSE">GME</a>) shares fell 5.5% to $26.45, pulling back after rallying 21% on Monday.</li>
</ul>
Now Read This: <a href="https://www.benzinga.com/news/24/06/39157476/nvidia-to-rally-around-11-here-are-10-top-analyst-forecasts-for-tuesday">Nvidia To Rally Around 11%? Here Are 10 Top Analyst Forecasts For Tuesday</a>

Intraday Update

Markets

Movers

Trading Ideas

AGEN

ALBT

ANNX

ARCH

BARK

BBWI

CAMP

CAPT

CBUS

CCLD

Core Scientific, Inc. - Class A Common Stock

CORZ

DAVE

FWRD

GCTS

HLVX

HUMA

JDZG

MBOT

MITQ

MLGO

MRIN

NDRA

NIVF

OBLG

SAIA

SINT

SKYW

SOBR

WIMI

WULF

YGMZ

ZLAB

Why Core & Main Shares Are Trading Lower By 11%? Here Are Other Stocks Moving In Tuesday's Mid-Day Session

Amarin shares are trading lower after the company announced that it appointed Aaron Berg as President and CEO.

Management

Amarin Has Appointed Aaron Berg, Currently Amarin's Executive Vice President And President Of The US Business, As President And Chief Executive Officer, Following The Resignation Of Patrick Holt As President & CEO Of The Company

Amarin Corporation Announces Greek Ministry Of Health Approval For National Reimbursement Of VAZKEPA To Reduce Cardiovascular Events In High-Risk Statin-Treated Adults

Amarin Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMRN#NASDAQ">AMRN</a>) reported quarterly losses of $(0.01) per share which beat the analyst consensus estimate of $(0.03) by 66.67 percent. This is a 150 percent decrease over earnings of $0.02 per share from the same period last year. The company reported quarterly sales of $56.519 million which missed the analyst consensus estimate of $57.045 million by 0.92 percent. This is a 34.26 percent decrease over sales of $85.975 million the same period last year.

Amarin Corp Q1 2024 Adj EPS $(0.01) Beats $(0.03) Estimate, Sales $56.519M Miss $57.045M Estimate

<h3>Gainers</h3>
<ul>
<li>Acrivon Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ACRV#NASDAQ">ACRV</a>) stock rose 12.3% to $10.67 during Wednesday's after-market session. The market value of their outstanding shares is at $329.4 million. </li>
<li>Amarin Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMRN#NASDAQ">AMRN</a>) stock moved upwards by 8.12% to $0.95. The company's market cap stands at $381.2 million. </li>
<li>Universe Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/UPC#NASDAQ">UPC</a>) stock rose 7.47% to $2.3. The market value of their outstanding shares is at $8.3 million. </li>
<li>China Pharma Holdings, Inc. Common Stock (AMEX:<a class="ticker" href="https://www.benzinga.com/stock/CPHI#AMEX">CPHI</a>) shares moved upwards by 7.14% to $0.34. </li>
<li>Telesis Bio (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TBIO#NASDAQ">TBIO</a>) shares moved upwards by 7.12% to $0.34. The company's market cap stands at $10.3 million. </li>
<li>Aesthetic Medical Intl (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AIH#NASDAQ">AIH</a>) shares moved upwards by 6.98% to $0.49. The market value of their outstanding shares is at $23.3 million. </li>
</ul>
<h3>Losers</h3>
<ul>
<li>Akili (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AKLI#NASDAQ">AKLI</a>) shares decreased by 11.3% to $0.22 during Wednesday's after-market session. The company's market cap stands at $17.2 million. </li>
<li>BiomX (AMEX:<a class="ticker" href="https://www.benzinga.com/stock/PHGE#AMEX">PHGE</a>) shares fell 5.24% to $0.32. The company's market cap stands at $17.7 million. </li>
<li>OneMedNet (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ONMD#NASDAQ">ONMD</a>) stock fell 4.84% to $0.55. The company's market cap stands at $13.1 million. </li>
<li>Dare Bioscience (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DARE#NASDAQ">DARE</a>) shares decreased by 3.68% to $0.28. The company's market cap stands at $27.7 million. </li>
<li>Mereo BioPharma Group (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MREO#NASDAQ">MREO</a>) stock fell 3.6% to $2.68. The company's market cap stands at $375.8 million. </li>
<li>Biomarin Pharmaceutical (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BMRN#NASDAQ">BMRN</a>) shares fell 3.49% to $88.02. The market value of their outstanding shares is at $16.7 billion. The company's, Q1 earnings came out today. 
See Also: <a href="http://www.benzinga.com/money/best-healthcare-stocks/" title="www.benzinga.com/money/best-healthcare-stocks/">www.benzinga.com/money/best-healthcare-stocks/</a></li>
</ul>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

ACRV

AKLI

BMRN

CPHI

DARE

MREO

ONMD

PHGE

TBIO

12 Health Care Stocks Moving In Wednesday's After-Market Session

Amarin Corporation plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMRN#NASDAQ">AMRN</a>) today highlighted three data presentations at ACC.24 showcasing the mechanistic activity of Eicosapentaenoic&nbsp;acid (EPA), including the potential effects&nbsp;of EPA on endothelial cell dysfunction and&nbsp;on oxidation of samples enriched with&nbsp;Lp(a). &nbsp;
"The data presented at ACC.24 provide new evidence surrounding the mechanism of action for VASCEPA/VAZKEPA, including the effect of the compound in combination with high-intensity statin on endothelial cell function during inflammation and the compound's effect on Lp(a) levels," said R. Preston Mason, Ph.D., Brigham and Women's Hospital. "These learnings further advance understanding of how EPA and VASCEPA/VAZKEPA work to reduce cardiovascular events in at-risk patients."
The studies and their key findings are outlined below:
<a href="https://www.globenewswire.com/Tracker?data=D1yv06SPeRXPm1LDfFTlhIn4v1ywsbfHRKsg3KEWUdM_bJjV2ye5w_5l-__Sxu-Db3Y6GSWClFIEPzabM8B5a7aqSvIFvo0Ya5KnAmNfkIt3enYZL1ahMNXV10Z72O278Ef4UZHwOcybCr1iQpkcAUWW-Kf175RHfDsF_gemhZNxilA7bp1cYErOzrxANwyqt4Jt6OIoGentE0X4s4K0uxrQLASYynk9MW9TMlO9XcepBsVY2GF5zgVjloaW0ZDiFyvgdgh-JWQIGGdEkJ7s1y-4bx9W8VmkFeDcFlv1e9zyvflya99jqQvQ8oEVXyN0Zm5kX6JUhFoSEwemUvHD8tQK2OOLHkFLjkAjgzaPcumxRVmUNz5mW57qp2Ip5Q1_">Eicosapentaenoic&nbsp;acid (EPA) and a High Intensity Statin&nbsp;Enhanced Expression of Proteins for Detoxification of&nbsp;Reactive Oxygen Species during Angiotensin II Challenge in&nbsp;Endothelial Cells</a>
This analysis measured the separate and combined effects of EPA and&nbsp;rosuvastatin on expression of proteins involved in detoxification in&nbsp;vascular endothelial cells under inflammatory conditions with angiotensin II&nbsp; (Ang II).
The combination of&nbsp;EPA and rosuvastatin favorably modulated the expression of proteins related to oxidative stress and detoxification under disease-like conditions.&nbsp;These findings indicate that the&nbsp;net benefits of a high intensity statin and EPA, compared to statin alone, on&nbsp;expression of detoxification proteins during inflammation may contribute to&nbsp;reduced atherothrombotic risk in outcome trials.
<a href="https://www.globenewswire.com/Tracker?data=D1yv06SPeRXPm1LDfFTlhGKpwfwzzKo-UJWjdrrJX682o-H-uoE3r1vhxel2OjF0mj18XttQr2JcAaUEPlmIUPOhyAuqEdzFu4CDbUAIbyAX3uDYPJUYI51iqC6d7uHnIP2dzpTdUhHjC-8ySpq21_0Abdc8DQS31fiVvT1BVmWXvatHvT5VW4yIeme8IwU164H4zVUBPAO7gwg5PG9lQGaRm9IvYogNeR6nVxx7ElkOg1o7U8GerQQTp3vJCt8i7LJ5Ii0jvateA4ltpiMDBYBZ_yyNvZbqd6sEMEyXchiCXT3vUQq0gdkEFZwjknbsuYcikSorRHRQ1T5dxLUBeNwEXuywzgWeCWC-3IhgnTU=">Eicosapentaenoic&nbsp;Acid (EPA) and Rosuvastatin Modulate&nbsp;Expression of Endothelial Proteins that Regulate Function and&nbsp;Platelet Activity during Angiotensin II Stimulation&nbsp;</a>
In this analysis, investigators compared the separate and combined effects of EPA and rosuvastatin on expression of proteins that regulate platelet signaling and nitric oxide (NO) levels in human umbilical vein endothelial cells (HUVECs) subjected to angiotensin II (Ang II) stimulus.
The combination of EPA and rosuvastatin favorably modulated proteins involved in platelet degranulation and NO bioavailability in HUVECs under inflammatory conditions to a greater extent than their separate treatments. The beneficial effects of a high intensity statin and EPA on endothelial dysfunction may contribute to reduced atherothrombotic risk in outcome trials.
<a href="https://www.globenewswire.com/Tracker?data=D1yv06SPeRXPm1LDfFTlhGKpwfwzzKo-UJWjdrrJX69D4wJmgOkGikhog-PUnfmx7d9HJCnWBXAZYOnziWvlehnwT7mXQZxVeT81RiEJQww4ICdi283JtFhQgJghrC8jY_3RXSEoJ1kJNfLlxrrZeN_PLRxdrnKQlbL3OFYv6z-DYE2tiibOv_F7IzPVLsS94Nng1YFBg7ALrYatca5298gZ8V0u6msdv9KY2Q48jvWehnhADbGhbrWolLs7Wza0GM8bdI14zCYw4d_aqWUELw==">Eicosapentaenoic&nbsp;Acid (EPA) Inhibits Lipoprotein(a) [Lp(a)] Oxidation due to Scavenging Mechanisms In Vitro</a>
Elevated&nbsp;Lp(a) levels are an independent and causal risk factor for cardiovascular (CV) disease with limited treatments available. Oxidized&nbsp;Lp(a) stimulates&nbsp;foam cell formation, endothelial dysfunction, and inflammation.&nbsp;​
In this analysis, investigators tested EPA effects on oxidation of samples enriched with Lp(a) compared to the fully saturated eicosaenoic acid (EA; 20:0) and Trolox, a water-soluble analog of Vitamin E.
Investigators found that EPA inhibited oxidation of&nbsp;Lp(a) enriched plasma in a time-dependent fashion consistent with a free radical scavenging mechanism. The potent&nbsp;antioxidant actions of EPA may contribute to reduced CV events in REDUCE-IT, including among those subjects with elevated&nbsp;Lp(a).

Amarin Highlights Key Data Providing Mechanistic Insights Into Eicosapentaenoic Acid At ACC.24

Reported Saturday, New REDUCE-IT Analyses By Amarin Show That VASCEPA/VAZKEPA Benefits High-Risk Cardiovascular Disease Patient Subgroups

Amarin shares are trading higher. The company announced it received a Decision to Grant from the European Patent Office for a new patent covering VAZKEPA that will extend VAZKEPA exclusivity eight additional years into 2039.

Amarin ( ($AMRN) ) just unveiled an announcement. Tom Reilly has stepped down from his role as Executive Vice President, Chief Financial Officer, a...

Amarin Executive VP and CFO Tom Reilly Steps Down

Warning: AMRN is at high risk of performing badly

Amarin Q3 2024 Earnings Preview

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These names in the biotech sector are seeing a substantial increase in search activity today, as determined by InvestingChannel. They include:&nbsp...

Biotech Alert: Searches spiking for these stocks today

Amarin Non-GAAP EPS of -$0.05 beats by $0.01, revenue of $42.3M misses by $2.21M

Amarin Corporation plc 2024 Q3 - Results - Earnings Call Presentation

Amarin Corporation plc (AMRN) Q3 2024 Earnings Call Transcript

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Press Releases

Amarin Board of Directors Announces CEO Transition

Amarin Partner EddingPharm Receives Regulatory Approval for VASCEPA® (Icosapent Ethyl) in Mainland China for Cardiovascular Risk Reduction (CVRR)

Amarin to Report Second Quarter 2024 Financial Results and Host Conference Call on July 31, 2024

Amarin Receives National Reimbursement for VAZKEPA® (icosapent ethyl) in Portugal

HLS Announces Reimbursement for Vascepa® under Alberta's Provincial Drug Plan

Amarin Reports Second Quarter 2024 Financial Results and Provides Business Update

Latest Research Highlighting VASCEPA®/VAZKEPA® (icosapent ethyl) REDUCE-IT® Subgroup Data and New Mechanistic Insights into Eicosapentaenoic Acid (EPA) to be Presented at European Society of Cardiology (ESC) Congress

Research Highlighting the Clinical Impact of VASCEPA®/VAZKEPA (icosapent ethyl) in Patients with Diabetes and High Cardiovascular Risk and the Anti-Lp(a) Oxidation Mechanistic Effect of Eicosapentaenoic Acid (EPA) to be Presented at the 60th Annual European Association for the Study of Diabetes (EASD) Meeting

Amarin Announces Two Upcoming Investor Events

Amarin Reports Third Quarter 2024 Financial Results and Provides Business Update

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