La catena delle opzioni mostra i dati chiave delle opzioni azionarie di AN2 Therapeutics a vari prezzi di esercizio e date di scadenza. I trader utilizzano queste informazioni per analizzare potenziali operazioni e valutare il sentiment del mercato per AN2 Therapeutics..

AN2 Therapeutics (NASDAQ:ANTX) Azioni, Catena delle Opzioni

AN2 THERAPEUTICS INC

Anthem

AN2 Therapeutics

AN2 Therapeutics Inc is a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform. The company has a pipeline of boron-based compounds in development for Chagas disease, non-tuberculous mycobacterial (NTM) and melioidosis, along with early-stage programs focused on targets in infectious diseases and oncology.

AN2 Therapeutics Inc

Needham analyst Mayank Tandon reiterates International Money (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/IMXI#NASDAQ">IMXI</a>) with a Buy and maintains $20 price target.

News

Price Target

Reiteration

Analyst Ratings

IMXI

Needham Reiterates Buy on International Money, Maintains $20 Price Target

Healthcare Realty Trust Incorporated (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/HR#NYSE">HR</a>) ("Healthcare Realty" or the "Company") today announced that its Board of Directors ("Board") has unanimously appointed Peter A. Scott to be the Company's President and Chief Executive Officer following an extensive and rigorous search process.&nbsp; He will be based at the Company's Nashville headquarters and assume his new role on April 15, 2025.&nbsp;Mr. Scott is expected to be added to the Board following the Company's 2025 annual meeting of stockholders.
Since 2017, Mr. Scott served as Chief Financial Officer of Healthpeak Properties, Inc., an S&amp;P 500 company with approximately $25 billion of assets that primarily owns and develops healthcare real estate for outpatient medical and life science tenants.&nbsp; Before joining Healthpeak, he was a Managing Director in the Real Estate Investment Banking Group at Barclays.&nbsp;
Connie Moore, who has served as Interim President and CEO of the Company since November 2024, will transition out of that role and continue to serve on the Board.&nbsp;&nbsp;&nbsp;&nbsp;

Management

Healthcare Realty Names Healthpeak CFO Peter Scott as New CEO, Succeeding Interim Chief Connie Moore

Steve Jobs never hesitated to ask for help—even from people he had never met. In a 1994 interview, the Apple co-founder shared, "I've never found anybody that didn't want to help me if I asked them for help." It is a simple truth, yet many people struggle to implement it in their personal and professional lives.
What happened: When he was 12, Jobs opened the phone book, found HP co-founder Bill Hewlett's number, and cold-called him requesting leftover electronic parts. Hewlett was impressed, giving him both the parts and a summer internship in the assembly line. That brave ask became Jobs' first step into the world of tech.
Reminiscing, Jobs said: "I've always found something to be very true, which is most people don't get those experiences because they never ask."
See Also: <a href="https://in.benzinga.com/25/03/44555488/steve-jobs-didnt-fear-decision-fatigue-because-of-this-routine-now-gen-z-is-copying-his-outfit-playbook-to-stay-sane-stay-employed-and-stay-out-of-trouble-but-apple-co-founder-wasnt-the-only-one-with-this-peculiar-lifestyle-choice">Steve Jobs Detested Decision Fatigue, Now Gen Z Is Copying His Style Playbook To Stay Sane, Stay Employed And Stay Out Of Trouble</a>
Why it matters: According to Jobs, the barrier wasn't access—it was fear. "You've got to be willing to crash and burn, with people on the phone, with starting a company, with whatever. If you're afraid of failing, you won't get very far."
Jobs said in the interview that the difference between those who do things and those who dream of doing things lies in the ability to ask for help. So the next time you hesitate to reach out, remember—you might be one bold question away from changing your life.
Read Next: 
<ul>
<li><a href="https://in.benzinga.com/25/04/44627872/as-microsoft-turns-50-bill-gates-shares-the-original-code-that-started-it-all-that-was-the-revolution">Bill Gates Shares Original Code That Started It All As Microsoft Celebrates 50 Years: &#8216;That Was The Revolution&#8217;</a></li>
</ul>

Tech

Media

Steve Jobs Believed Help Is Always Available If You're Brave Enough To Reach Out: 'Most People Don't Get What They Want Because They Never Ask'

An old clip from The Men Who Built America is causing an uproar on social media as financial markets reel from Donald Trump's tariff policies.
In the 2012 History Channel mini-series, Trump said, "I find that I do better in bad markets," adding that downturns create the best buying opportunities. More than ten years later, critics are asking whether that approach is now playing out in real time in Trump's second presidential term.
What Happened: Trump has imposed extensive tariffs—ranging from 10% to 50%—on imports from dozens of countries, calling the move economic "medicine." Speaking aboard Air Force One on Sunday, Trump trivialized concerns over trillions in lost market value, saying, "Sometimes you have to take medicine to fix something", Reuters reports.
Global markets have gone haywire since the tariffs came into effect. Taiwan's benchmark index experienced its worst one-day drop in history. Japan's Nikkei faced an 18-month low, and oil prices collapsed.
See Also: <a href="https://in.benzinga.com/markets/equities/25/04/44659686/stock-futures-tank-dow-sheds-over-1000-points-as-white-house-remains-firm-on-tariffs-trump-says-sometimes-you-have-to-take-medicine">Stock Futures Tank, Dow Sheds Over 1000 Points As White House Remains Firm On Tariffs: Trump Says, &#8216;Sometimes You Have To Take Medicine&#8217;</a>
Why It Matters: Trump pitched the tariffs as a play to protect U.S. manufacturing and reshape trade norms—but the wider economic cost may be high. JP Morgan now predicts that the U.S. economy will shrink this year. Goldman Sachs cut back China's growth forecast.
Central banks in New Zealand and Indonesia are already preparing emergency strategies, according to Reuters.
This backdrop is giving fresh weight to Trump's decade-old comments. If asset values plunge and cash-rich investors move in to buy low, many fear this may be less of an unintentional side effect—and more of a playbook.
There is no direct proof that Trump is engineering an economic downturn. But the attitude outlined in the resurfaced quote, and the administration's readiness to absorb massive losses, has reignited conjecture. Critics argue that ordinary consumers endure the burdens of inflation and job losses, while the ultra-rich stand to gain if markets bottom out.
Read Next:
<ul>
<li><a href="https://in.benzinga.com/news/25/04/44658760/trumps-trade-war-intensifies-stirring-unease-among-republicans-and-corporate-america">Trump&#8217;s Trade War Intensifies, Stirring Unease Among Republicans and Corporate America</a></li>
</ul>
Photo courtesy: Shutterstock

Social Media

Markets

General

'I Do Better In Bad Markets': Trump's 2012 Comments Gain Steam As Tariff 'Medicine' Wrecks Global Stocks And Sparks Fears Of Deliberate Economic Fallout

Ascendiant Capital analyst Lucas Ward reiterates LiqTech Intl (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LIQT#NASDAQ">LIQT</a>) with a Buy and raises the price target from $3.2 to $3.4.

LIQT

Ascendiant Capital Reiterates Buy on LiqTech Intl, Raises Price Target to $3.4

On Friday, April 4th, U.S. markets closed sharply lower, marking Wall Street&#8217;s second consecutive day of steep losses. The Nasdaq officially entered a bear market, while the Dow slipped into correction territory amid intensifying global trade tensions.
President Trump&#8217;s sweeping tariffs sparked fears of a global recession, erasing trillions in market value. Investor panic surged as volatility spiked, and world leaders scrambled to coordinate responses to the escalating trade conflict.
In economic data, March U.S. nonfarm payrolls jumped by 228,000, beating forecasts and the recent average. February&#8217;s figure was revised down to 117,000. Unemployment rose slightly to 4.2%, against expectations of no change. Average hourly earnings grew 0.3% month-over-month and 3.8% year-over-year, just below the 3.9% forecast.
Most S&amp;P 500 sectors fell Friday, led by financials, energy, and tech, amid heightened volatility, while consumer staples rose as investors turned to defensive assets.
Also Read: <a target="_blank" href="https://www.benzinga.com/markets/equities/25/04/44659686/stock-futures-tank-dow-sheds-over-1000-points-as-white-house-remains-firm-on-tariffs-trump-says-sometimes-you-have-to-take-medicine" rel="noreferrer noopener">Stock Futures Tank, Dow Sheds Over 1000 Points As White House Remains Firm On Tariffs: Trump Says, &#8216;Sometimes You Have To Take Medicine</a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
The Dow Jones Industrial Average tumbled 5.5% to 38,314.86, while the S&amp;P 500 dropped 5.97% to 5,074.08. The Nasdaq Composite also fell sharply, losing 5.82% to close at 15,587.79.
Asia Markets Today
<ul>
<li>On Monday, Japan&#8217;s Nikkei 225 closed the session lower by 7.68% at 31,187.50, hitting a 1.5-year low, as fears of a global recession from Trump&#8217;s new tariffs triggered a broad selloff, especially in banks and chip-related stocks.</li>
<li>Australia&#8217;s S&amp;P/ASX 200 was down 4.23% and closed at 7,343.30, led by losses in the Energy, IT, and Consumer Discretionary sectors.</li>
<li>India&#8217;s Nifty 50 was down 2.84% to 22,252.90, and Nifty 500 declined 3.07% to 20,164.35.</li>
<li>China&#8217;s Shanghai Composite fell 7.34% to 3,096.58, and Shanghai Shenzhen CSI 300 declined 7.05% to 3,589.44.</li>
<li>Hong Kong&#8217;s Hang Seng Index plummeted 13.2% to 19,828.30, marking its worst single-day drop since 1997. Escalating U.S.-China tariffs intensified trade war fears, sparking a broad selloff in tech and growth-linked sectors and roiling global markets.</li>
</ul>
Eurozone at 05:45 AM ET
<ul>
<li>The European STOXX 50 was down 5.63%.</li>
<li>Germany&#8217;s DAX declined 5.84%.</li>
<li>France&#8217;s CAC 40 fell 5.76%.</li>
<li>U.K.&#8217;s FTSE 100 index traded lower by 4.74%.</li>
<li>European markets tumbled as Trump&#8217;s unwavering tariff stance and rising U.S.-China tensions deepened fears of a global recession. Already grappling with weak industrial data, Europe faced added pressure from looming EU retaliatory tariffs and sharp losses in banking and energy stocks.</li>
</ul>
Commodities at 05:45 AM ET
<ul>
<li>Crude Oil WTI was trading lower by 3.89% at $59.58/bbl, and Brent was down 3.67% at $63.16/bbl.</li>
<li>Oil prices fell as U.S.-China trade tensions stoked recession fears, weakening demand outlook. Additionally, Saudi price cuts and OPEC+ plans to boost output intensified pressure on crude benchmarks.</li>
<li>Natural Gas slid 3.08% to $3.719.</li>
<li>Gold was trading higher by 0.21% at $3,041.50, Silver was up 3.22% to $30.170, and Copper fell 1.28% to $4.3420.</li>
<li>Gold prices fell to a three-week low as investors liquidated positions to cover losses from a broader market selloff, which was driven by Trump&#8217;s sweeping tariffs and rising global recession fears despite gold&#8217;s safe-haven status.</li>
</ul>
U.S. Futures at 05:45 AM ET
Dow futures were down 3.05%, S&amp;P 500 futures declined 3.13%, and Nasdaq 100 futures slid 3.46%.
Forex at 05:45 AM ET
The U.S. Dollar Index declined 0.11% to 102.88, USD/JPY was down 0.59% to 146.03, and USD/AUD gained 0.54% to 1.6626.
Photo by Skorzewiak via Shutterstock

Asia

Emerging Markets

Eurozone

Futures

Commodities

Forex

Movers

ADIV

AGOV

ASHR

BBEU

BOIL

CQQQ

PowerShares DBmmodity Index Optimum Yield Diversified Fund

EEMA

FLAX

CurrencyShares British Pound Sterling Trust

IEMG

IEUR

KraneShares Trust KraneShares S&P Pan Asia Dividend Aristocrats Index ETF

KDIV

SPEM

USDU

PowerShares DB US Dollar Index Bullish Fund

Global Markets See Worst Drop Since 1997 Mimicking Black Monday Like Crash, Crude Oil Tumbles

After exiting college in 2007 with $50,000 in student loans and no degree in hand, Amy Landino was financially insecure and unsure about the future. Almost two decades later, she's raking in $8,200 a month in passive income — all while putting in just four hours of work a day.
In a recent profile for CNBC Make It, the content creator and group coach shared what she's learned on her journey to building a sustainable business — and what people misunderstand about passive income.
What Happened: Landino created her brand with over a thousand YouTube videos on productivity and personal branding. "It takes consistent upkeep and creative planning," she told CNBC Make It. Behind each video lies hours of prep and filming, and older content needs to be updated regularly to keep providing value to viewers.
She got her first taste of automated earnings through a straightforward video course that brought in $1,000 in one day, with just one email to a small pool of subscribers. "I started with a camera I already owned," she said.
Why It Matters: As Landino shifts her attention towards coaching, she is countering what she calls the top three "complete lies" about passive income: that it takes no work, that it requires a huge budget, and that it sustains itself forever. In reality, she notes, successful income streams depend on maintaining connection with your audience, putting systems in place, and offering products that evolve according to their needs.
Throughout her journey, from self-publishing Vlog Like a Boss to creating a morning routine planner inspired by fan requests, Landino has relied on her community to direct each new step.
"Passive income doesn't mean set-it-and-forget-it," she said. "It means being strategic about how you show up — and creating things that keep working, even when you're not."
Read Next:
<ul>
<li><a href="https://www.benzinga.com/25/04/44661965/trumps-reciprocal-tariff-threat-wipes-out-nearly-18-trillion-from-magnificent-7-dan-ives-warns-it-could-set-us-tech-back-a-decade-investors-know-math-and-the-sad-reality">Trump&#8217;s &#8216;Reciprocal&#8217; Tariff Threat Wipes Out Nearly $1.8 Trillion From Magnificent 7, Dan Ives Warns It Could Set US Tech Back A Decade: &#8216;Investors Know Math And The Sad Reality&#8217;</a></li>
</ul>
Photo courtesy: Shutterstock

Entertainment

Education

This Youtuber Went From College Dropout To Earning $8,200 A Month In Passive Income By Working Just 4 Hours A Day: And The 3 Biggest Lies She Wants You To Stop Believing About Making Money While You Sleep

RPM International Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/RPM#NYSE">RPM</a>) will release earnings results for the third quarter, before the <a href="https://www.benzinga.com/quote/RPM/earnings">opening bell on Tuesday, April 8.</a>
Analysts expect the Medina, Ohio-based company to report quarterly earnings at 50 cents per share, down from 52 cents per share in the year-ago period. RPM projects to report quarterly revenue at $1.51 billion, compared to $1.52 billion a year earlier, according to data from <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>.
On April 3, RPM International reported that it has signed a definitive agreement to acquire U.K.-based Star Brands Group, the maker of The Pink Stuff, for its Rust-Oleum subsidiary.
RPM shares tumbled 3.9% to close at $108.23 on Friday.
Benzinga readers can access the latest analyst ratings on the <a href="https://www.benzinga.com/analyst-ratings/analyst-color/22/09/28888638/exclusive-study-finds-benzinga-analyst-ratings-data-yields-market-beating-strategie">Analyst Stock Ratings</a> page. Readers can sort by stock ticker, company name, analyst firm, rating change or other variables.
Let's have a look at how Benzinga's most-accurate <a href="https://www.benzinga.com/quote/RPM/analyst-ratings">analysts have rated the company</a> in the recent period.
<ul>
<li>JP Morgan analyst Jeffrey Zekauskas maintained a Neutral rating and cut the price target from $126 to $124 on Jan. 8, 2025. This analyst has an accuracy rate of 67%.</li>
<li>Mizuho analyst John Roberts maintained an Outperform rating and cut the price target from $150 to $140 on Jan. 8, 2025. This analyst has an accuracy rate of 75%.</li>
<li>Wells Fargo analyst Michael Sison upgraded the stock from Equal-Weight to Overweight and raised the price target from $134 to $140 on Jan. 8, 2025. This analyst has an accuracy rate of 66%.</li>
<li>Morgan Stanley analyst Vincent Sinisi maintained an Equal-Weight rating and boosted the price target from $107 to $125 on Oct. 4, 2024. This analyst has an accuracy rate of 73%.</li>
<li>Seaport Global analyst Michael Harrison maintained a Buy rating and increased the price target from $140 to $150 on Oct. 3, 2024. This analyst has an accuracy rate of 67%.</li>
</ul>
Considering buying RPM stock? Here&#8217;s what analysts think: 
<figure class="wp-block-image size-large is-resized"><img loading="lazy" decoding="async" width="1024" height="596" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/07063944/image-54-1024x596.png" alt="" class="wp-image-859635" style="width:605px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/07063944/image-54-1024x596.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/07063944/image-54-300x175.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/07063944/image-54-768x447.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/07063944/image-54.png 1117w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
Read This Next: 
<ul>
<li><a href="https://www.benzinga.com/analyst-ratings/price-target/25/04/44645517/wall-streets-most-accurate-analysts-give-their-take-on-3-health-care-stocks-with-over-4-dividend-yields-2">Wall Street&#8217;s Most Accurate Analysts Give Their Take On 3 Health Care Stocks With Over 4% Dividend Yields</a> </li>
</ul>
Photo via Shutterstock

Earnings

Trading Ideas

RPM Gears Up For Q3 Print; Here Are The Recent Forecast Changes From Wall Street's Most Accurate Analysts

Goldman Sachs Group Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GS#NYSE">GS</a>) is the latest investment bank to predict a recession for the U.S. economy over the next 12 months, with the odds being raised to 45%, from its previous prediction of 35%. Amidst <a href="https://www.benzinga.com/25/04/44662164/us-stock-futures-slump-following-massive-tariff-induced-selloff-experts-warn-of-a-brewing-great-depression-like-pattern">all this chaos and uncertainty</a>, however, there is a silver lining for the tech giants and their executives.
What Happened: On Sunday night, Goldman Sachs published a note raising its recession probability forecast from 35% to 45%, citing the sharp tightening of financial conditions and a spike in policy uncertainty. Just a month ago, it raised the probability from 20% to 35%, stating that economic fundamentals weren&#8217;t as robust as in the prior years.
See More: <a href="https://www.benzinga.com/25/04/44662249/end-of-cheap-clothing-era-tariffs-to-hit-apparel-industry-hard">Tariffs Threaten To End Era Of Cheap Clothing — Apparel Industry Faces Major Price Shock Under Trump Policy</a>
The bank now follows JPMorgan Cash &amp; Co. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/JPM#NYSE">JPM</a>), which <a href="http://benzinga.com/economics/macro-economic-events/25/04/44645681/jpmorgan-raises-recession-risk-to-60-as-largest-us-tax-hike-in-60-years-hits-global-economy">made a similar prediction last week</a>, hiking the odds of a global recession to 60%.
While none of this sounds good, Jefferies Financial Group Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/JEF#NYSE">JEF</a>) analysts believe that this, along with the Donald Trump administration&#8217;s tariffs, can be a &#8216;Free Hall Pass&#8217; for tech companies to revamp their financial guidance.
According to the firm&#8217;s lead analyst Brent Thill, companies can use this crisis to aim for &#8216;lower estimates that are more achievable and can help boost investor sentiments and stock performance,&#8217; as <a href="https://markets.businessinsider.com/news/stocks/tariffs-free-hall-pass-to-reset-big-tech-profit-guidance-2025-4">reported</a> by Business Insider. 
The firm&#8217;s analysts then cut their Price Targets for Amazon.com Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMZN#NASDAQ">AMZN</a>), Meta Platforms Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/META#NASDAQ">META</a>), and Microsoft Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MSFT#NASDAQ">MSFT</a>), among 29 leading tech stocks.
Why It Matters: The analysts noted that besides the obvious first and second order impacts of the tariffs, both Meta and Amazon generate significant revenue from Chinese advertisers trying to reach global audiences, which is now under pressure.
However, analysts have asked the tech giants to use this as an opportunity to reset their guidance to move conservative figures, something that better reflects new market realities.
Read More:
<ul>
<li><a href="https://www.benzinga.com/markets/equities/25/04/44661978/bill-ackman-blames-market-collapse-on-tariff-timing-says-trump-advisor-should-be-fired-now-predicts-a-lot-more-than-5-dip">Bill Ackman Blames Market Collapse On Tariff Timing, Says Trump Advisor &#8216;Should Be Fired Now:&#8217; Predicts &#8216;A Lot More Than 5%&#8217; Dip</a></li>
</ul>
Photo courtesy: Shutterstock

Large Cap

Economics

AMZN

MSFT

Goldman Sachs Raises Risk Of Recession to 45%: Jefferies Calls Tariffs a 'Free Hall Pass' For Tech Giants To Reset Their Goals

New Gold Inc. ("New Gold" or the "Company") (TSX:<a class="ticker" href="https://www.benzinga.com/stock/NGD#TSX">NGD</a>) (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/NGD#NYSE">NGD</a>) is pleased to announce that it has entered into an agreement with Ontario Teachers' Pension Plan ("Ontario Teachers'") to acquire the remaining 19.9% free cash flow interest in the Company's New Afton Mine ("New Afton") (the "Transaction"). Following the transaction, the Company will have fully consolidated its free cash flow interest in New Afton to 100%.
On closing of the Transaction, Ontario Teachers' free cash flow interest in New Afton will be fully eliminated in exchange for a cash payment of $300 million from New Gold. New Gold plans to fund the cash payment with cash on hand, borrowings from its existing revolving credit facility and a gold prepayment financing ("Gold Prepayment").
Benefits to New Gold Shareholders
<ul>
<li>Fully consolidates free cash flow from one of Canada's most attractive mines&nbsp;– New Afton is entering into a period of expected significant free cash flow growth driven by increasing production and improved costs.</li>
<li>Investment in an existing high-quality operation&nbsp;– New Gold has developed extensive block caving expertise and social partnerships in an exceptional location.</li>
<li>Accretive and disciplined transaction&nbsp;– Fully consolidates ownership, gaining exposure to 100% of New Afton's life-of-mine cash flow with no equity dilution to New Gold's shareholders. New Gold will finance the Transaction by utilizing its strong balance sheet and significant near-term free cash flow, while maintaining financial discipline and flexibility.</li>
<li>Increased upside exposure&nbsp;– New Gold's focus on near-mine exploration activities, highlighted by exceptional drill results released in September 2024, provides New Afton with the potential to add substantial value by improving the production profile and extending mine life.&nbsp;The Company is committing $17 million towards exploration in 2025, with a strong focus on K-Zone.</li>
</ul>

TSX:NGD

New Gold To Buy Remaining 19.9% Stake in New Afton Mine for $300M in Cash

Parsons Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/PSN#NYSE">PSN</a>) announced today that the company was awarded a biological defense research contract to advance the Naval Medical Research Command's (NMRC) mission to defend against the threat of biological and chemical warfare. The $24 million contract consists of a one-year base period and four one-year option periods.
Under this contract, Parsons will continue to support NMRC's Biological Defense Research Directorate (BDRD) in their efforts to facilitate biological research for the rapid detection of infectious diseases of Department of Defense importance and the enhancement of global disease surveillance for early pathogen detection and response.

Government

Regulations

Parsons Lands $24M Navy Contract to Advance US Biological Defense Research

Billionaire Investor Bill Ackman has criticized Commerce Secretary Howard Lutnick of having a conflict of interest and being &#8220;indifferent&#8221; toward the stock market selloff induced by the introduction of tariffs because of the latter&#8217;s fund, Cantor Fitzgerald LP&#8217;s exposure to bond investors.
What Happened: Ackman, the CEO of Pershing Square Capital Management, L.P., has slammed. Lutnick, who was the former chairman and CEO of Cantor Fitzgerald L.P. by stating that &#8220;He (Lutnick) profits when our economy implodes.&#8221;
This aligns with the inverse relationship between stocks and bonds during economic crises. When stocks crash, investors often move capital into bonds, driving up bond prices and lowering yields.
As the markets continue to crash after President Donald Trump&#8217;s tariffs, the 10-year Treasury yield has fallen to 3.90%. It is the first time that the yield has fallen to this level since before Trump was elected last year in October. Meanwhile, the two-year yield has dropped to 3.45%.
Cantor Fitzgerald, on the other hand, has been a major player in bond markets since its founding in 1945.
&#8220;It's a bad idea to pick a Secretary of Commerce whose firm is levered long fixed income. It's an irreconcilable conflict of interest,&#8221; added Ackman in his post.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">I just figured out why <a href="https://twitter.com/howardlutnick?ref_src=twsrc%5Etfw">@howardlutnick</a> is indifferent to the stock market and the economy crashing. He and Cantor are long bonds. He profits when our economy implodes. It's a bad idea to pick a Secretary of Commerce whose firm is levered long fixed income. It's an irreconcilable…
&mdash; Bill Ackman (@BillAckman) <a href="https://twitter.com/BillAckman/status/1909069404694065350?ref_src=twsrc%5Etfw">April 7, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
See Also: <a href="https://www.benzinga.com/25/04/44661029/trump-and-fed-stand-firm-lack-of-a-put-could-drive-the-market-lower-very-quickly-warns-expert">Lack Of &#8216;Trump Put&#8217; Could Drive Market Lower &#8216;Very Quickly,&#8217; Says Expert, As Fed Chair Jerome Powell Stands Ground On Rate Cuts</a>
Why It Matters: According to Cantor Fitzgerald&#8217;s 13F filings, it holds positions in 275 publicly traded equity and debt securities, but has no significant exposure to bonds or bond-linked ETFs. However, the company is long bonds indirectly via these channels.
<ul>
<li>Primary Dealer Role: As one of the 24 primary dealers, Cantor Fitzgerald must participate in Treasury auctions and maintain an active market, necessitating long bond positions not reported on 13F.</li>
</ul>
<ul>
<li>Long Bond Fund: Cantor Fitzgerald&#8217;s Ireland-based Long Bond Fund invests in longer-dated Eurozone government bonds, representing a separate long bond position not typically on the 13F.</li>
</ul>
<ul>
<li>Infrastructure Fund: The Cantor Fitzgerald Infrastructure Fund allocates 30% to public infrastructure equity and debt, but specific holdings aren&#8217;t in the 13F, as 70% is in private investments.</li>
</ul>
Furthermore, Ackman, in replies to his post, claims that his position is &#8220;long America,&#8221; aligning his interests with the country's economic growth, while portraying Lutnick as &#8220;short America&#8221; due to his bond-heavy stance.
President Donald Trump&#8216;s post-market close tariff announcement on Wednesday ignited a dramatic market selloff on Thursday, exacerbated by China&#8217;s retaliatory measures on Friday.
As of Friday, the S&amp;P 500 was nearing the bear market zone as it closed 17.46% lower than its previous record high of 6,147.43 points. Dow was 14.99% down from its 52-week high of 45,073.63 points, whereas the Nasdaq 100 was already in the bear market territory, 21.71% lower from its high of 22,222.61 points.
Price Action: The SPDR S&amp;P 500 ETF Trust (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SPY#NYSE">SPY</a>) and Invesco QQQ Trust ETF (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/QQQ#NASDAQ">QQQ</a>), which track the S&amp;P 500 index and Nasdaq 100 index, respectively, slumped in premarket on Monday. SPY was down 3.39% and QQQ declined 3.64%.
On Friday, the SPY closed down 5.85% to $505.28, while the QQQ ended 6.21% lower to $422.67, according to <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a> data.
Read Next:
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<li><a href="https://www.benzinga.com/general/market-summary/25/04/44660779/sp-500-dow-jones-on-course-to-mimic-rare-consecutive-losses-not-seen-since-the-great-depre">S&amp;P 500, Dow Jones On Course To Mimic Rare Consecutive Losses Not Seen Since The Great Depression: What&#8217;s Driving the Fear?</a></li>
</ul>
Photo courtesy: Shutterstock

Equities

Market Summary

Bonds

Hedge Funds

Treasuries

ETFs

Bill Ackman Slams Commerce Secretary Howard Lutnick For Ignoring Stock Market Crash: 'He And Cantor Are Long Bonds'

On Monday, analyst Ming-Chi Kuo cautioned that President Donald Trump's tariff policy could pose significant near-term risks to semiconductor stocks, highlighting that even Apple Inc.'s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AAPL#NASDAQ">AAPL</a>) <a href="https://in.benzinga.com/news/25/03/44109824/apples-500b-u-s-investment-analyst-calls-it-completely-unrealistic-questions-where-the-money-will-come-from">$500 billion U.S. investment</a> couldn&#8217;t secure leniency from the administration's aggressive approach.
What Happened: Kuo took to X and expressed concerns about the impact of the Trump administration&#8217;s potential semiconductor tariff policies. 
"I'm taking a cautious stance on the upcoming semiconductor tariff policy under the Trump administration. Investors should stay alert to the near-term risks surrounding semiconductor stocks," Kuo said.
He indicated that the administration's reliance on tariffs as a tool to bring manufacturing back to the U.S. might lead to challenges for semiconductor companies.
Kuo pointed to Apple as a key case study in this context. Despite its substantial efforts to shift its supply chain away from China during Trump's first term and its $500 billion investment in the U.S., Apple did not escape tariffs.&nbsp;
See Also:&nbsp;<a href="https://www.benzinga.com/news/legal/25/04/44620411/mark-zuckerberg-led-meta-set-to-face-truth-at-senate-hearing-over-china-operations-and-communist-party-censorship-efforts" target="_blank" rel="noreferrer noopener">Mark Zuckerberg-Led Meta Set To Face ‘Truth' At Senate Hearing Over China Operations And Communist Party Censorship Efforts</a>
"You'd think such efforts would earn some leniency, but they didn't," Kuo explained.
This raised critical questions about the approach to semiconductor tariffs, particularly for non-U.S. companies. "Have non-U.S. semiconductor companies done more than Apple to reduce their reliance on China in recent years?" Kuo asked. "Have they outpaced Apple in U.S. investments? Do these non-U.S. companies have stronger ties to the U.S. government than Apple?"
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">I&#39;m taking a cautious stance on the upcoming semiconductor tariff policy under the Trump administration. Investors should stay alert to the near-term risks surrounding semiconductor stocks. The Trump administration has consistently viewed tariffs as a tool to bring manufacturing…
&mdash; 郭明錤 (Ming-Chi Kuo) (@mingchikuo) <a href="https://twitter.com/mingchikuo/status/1909114544989106565?ref_src=twsrc%5Etfw">April 7, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
In response to a comment asking about the long-term trend of U.S. semiconductor manufacturing, Kuo suggested that while the short-term risks were clear, companies that align strategically with the U.S. could benefit in the long run.&nbsp;
"Winners and losers are another big deal. Before that, can see if the semi companies that invested in U.S. earlier can earn some leniency in the upcoming semi tariffs," Kuo added.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">Winners and losers are another big deal. Before that, can see if the semi companies that invested in U.S. earlier can earn some leniency in the upcoming semi tariffs.
&mdash; 郭明錤 (Ming-Chi Kuo) (@mingchikuo) <a href="https://twitter.com/mingchikuo/status/1909121287316033639?ref_src=twsrc%5Etfw">April 7, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
Why It Matters: Last week, Trump unveiled a new <a href="https://www.benzinga.com/economics/macro-economic-events/25/04/44626421/trumps-reign-of-tariffs-unleashes-d-day-on-wall-street-analyst-warns-of-stagflation-risk">wave of reciprocal tariffs</a>. The tariff strategy involved country-specific rates, such as 34% on Chinese goods and 32% on imports from Taiwan, alongside a flat 10% tariff on products from other nations.
However, the White House said that some items, like auto parts and steel, which are already facing separate tariffs, as well as energy and mineral resources not domestically available, would be exempt from this new policy.
Semiconductors also <a href="https://in.benzinga.com/news/global/25/04/44631606/trumps-tariff-exemptions-include-semiconductors-pharmaceuticals-oil-and-more">fall under the exemption list</a>, but according to Jefferies analysts, that&#8217;s likely because Trump is contemplating targeted tariffs for that sector.
While these measures aren&#8217;t directly affecting chips just yet, the analysts warned on Friday that they could still lead to rising costs for electronic devices and tech products that rely on semiconductors, thereby dampening overall demand.
Jefferies believes these tariffs will continue to put downward pressure on semiconductor stocks, including Nvidia Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVDA#NASDAQ">NVDA</a>), Advanced Micro Devices Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMD#NASDAQ">AMD</a>), and Broadcom Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AVGO#NASDAQ">AVGO</a>)— all of which rely heavily on chip manufacturing from Taiwan Semicndctr Mnufctrng Co. Ltd. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TSM#NYSE">TSM</a>).
Price Action: On Friday, Nvidia shares fell 7.36%, AMD dropped 8.57%, Broadcom (AVGO) slipped 5.01%, and TSMC declined 6.27%, according to <a href="http://pro.benzinga.com/">Benzinga Pro data</a>.
Read Next:
<ul>
<li><a href="https://www.benzinga.com/markets/25/01/43373775/tim-cook-praises-chinas-deepseek-for-driving-efficiency-stresses-apples-prudent-and-deliberate-approach-toward-capital-expenditure" target="_blank" rel="noreferrer noopener">Tim Cook Praises China's DeepSeek For Driving Efficiency, Stresses Apple's ‘Prudent And Deliberate' Approach Toward Capital Expenditure</a></li>
</ul>
Disclaimer: This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.
Photo courtesy: Shutterstock

AAPL

AVGO

NVDA

Ming-Chi Kuo Warns Semiconductor Stocks Face Near-Term Risks Under Trump Tariff Policy: Even Apple's $500 Billion US Investment Didn't Buy It Leniency

The cryptocurrency market has been caught up in President Donald Trump&#8217;s <a href="https://in.benzinga.com/25/04/44660141/odds-of-recession-federal-reserves-emergency-rate-cuts-soar-on-crypto-based-polymarket-as-tariff-fears-pummel-markets">tariff-induced recession fears</a>, with many coins falling sharply from their highs since the Republican took over the White House.
What happened: Since Trump's <a href="https://www.benzinga.com/government/regulations/25/01/43085323/trump-sworn-in-as-47th-president-declares-golden-age-of-america-begins-right-now">inauguration</a>, the total cryptocurrency market capitalization has shrunk by nearly 32%, with more than a trillion dollars in investors' wealth wiped out.
It's, therefore, hardly surprising that most coins, including the mega-cap ones, have traded in the red since his arrival.
Market barometer Bitcoin retreated from its $100,000 milestone, falling over 24% since Trump became president. This is despite the POTUS signing an executive order to <a href="https://in.benzinga.com/25/03/44183572/trump-establishes-strategic-bitcoin-reserve-funded-by-forfeited-assets-i-made-the-promise">create a Strategic Bitcoin Reserve</a>.
<figure class="wp-block-table"> 
<table>
<tbody>
<tr>
<td>Cryptocurrency</td>
<td>Price (Recorded on Jan. 20, 2025)</td>
<td>Price (Recorded at 4:30 a.m. ET)</td>
<td>Losses</td>
</tr>
<tr>
<td>Tron (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/trx/usd">TRX</a>)</td>
<td>$0.2281</td>
<td>$0.2237</td>
<td>1.9%</td>
</tr>
<tr>
<td>Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>)</td>
<td>$101,083.75</td>
<td>$76,281.52</td>
<td>24.53%</td>
</tr>
<tr>
<td>XRP (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/xrp/usd">XRP</a>)</td>
<td>$2.9544</td>
<td>$1.77</td>
<td>40%</td>
</tr>
<tr>
<td>Cardano (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/ada/usd">ADA</a>)</td>
<td>$0.9912</td>
<td>$0.5433</td>
<td>45.18%</td>
</tr>
<tr>
<td>Shiba Inu (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/shib/usd">SHIB</a>)</td>
<td>$0.00002027</td>
<td>$0.00001086</td>
<td>46.4%</td>
</tr>
<tr>
<td>Ethereum (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/eth/usd">ETH</a>)</td>
<td>$3,208.93</td>
<td>$1,499.31</td>
<td>53.27%</td>
</tr>
<tr>
<td>Solana (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/sol/usd">SOL</a>)</td>
<td>$250.62</td>
<td>$100.76</td>
<td>59.79%</td>
</tr>
<tr>
<td>Dogecoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/doge/usd">DOGE</a>)</td>
<td>$0.3577</td>
<td>$0.1383</td>
<td>61.3%</td>
</tr>
</tbody>
</table>
</figure>
See Also:<a href="https://www.benzinga.com/25/04/44621245/gold-backed-cryptos-match-yellow-metals-highs-following-trumps-liberation-day-shock"> Bitcoin Reeling From Trump&#8217;s &#8216;Liberation Day&#8217; Shock But These Gold-Backed Coins Are Killing It This Year</a>
Altcoins such as Ethereum, Solana, XRP, and Cardano, all of which Trump touted as being<a href="https://in.benzinga.com/25/03/44068814/bitcoin-ethereum-dogecoin-rally-on-trumps-strategic-crypto-reserve-announcement-cardano-x"> included in America&#8217;s cryptocurrency hoard</a>, have bled heavily, with SOL and ETH down more than 50% since the presidential inauguration.
Memecoin titan Dogecoin shed 61% of its value, becoming the biggest loser among large-cap cryptocurrencies.
The sentiment worsened after Elon Musk <a href="https://in.benzinga.com/markets/cryptocurrency/25/03/44554819/elon-musk-dismisses-dogecoin-use-by-government-clears-the-air-on-doge-department-two-very-different-things">ruled out the idea</a> of the U.S. government using Dogecoin for any purpose,&nbsp; a dampener for many enthusiasts, especially following the establishment of the Department of Government Efficiency.&nbsp;
On the brighter side, Tron's native token, TRX, has lost only about 2% since Trump assumed office. Investor confidence was likely boosted after the SEC submitted a joint motion <a href="https://in.benzinga.com/content/44543856/justin-sun-features-on-forbes-cover-talks-crypto-and-trump-linked-investments">asking a court to halt its lawsuit</a> against Sun and his companies.
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Photo courtesy: Shutterstock

Coverage of Bitcoin, Etherum, Ripple and all the latest digital currencies.

Cryptocurrency

$ADA

$BTC

$DOGE

$ETH

$SHIB

$SOL

$TRX

$XRP

Trump's Second Term Hasn't Been Favorable To The Crypto Market, But This Large-Cap Coin Holds Steady

Shares of Chanson International Holding (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CHSN#NASDAQ">CHSN</a>) rose sharply in today's pre-market trading after reported a year-over-year increase in <a href="https://www.benzinga.com/quote/chsn/earnings">FY24 financial results</a>.
Chanson International posted FY24 EPS of 5 cents, up from 3 cents per share in the year-ago period. The company's revenue surged to $18.2 million from $17.3 million.
Chanson International Holding shares jumped 170% to $0.5913 in pre-market trading
Here are some other stocks moving in pre-market trading.
<h3 class="wp-block-heading">Gainers</h3>
<ul>
<li>Bluejay Diagnostics, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BJDX#NASDAQ">BJDX</a>) rose 69.5% to $5.80 in pre-market trading after gaining over 7% on Friday.</li>
<li>SUNation Energy Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SUNE#NASDAQ">SUNE</a>) rose 28.3% to $0.2774 in pre-market trading after dipping 18% on Friday.</li>
<li>DevvStream Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DEVS#NASDAQ">DEVS</a>) surged 25.4% to $0.2496 in pre-market trading.</li>
<li>Professional Diversity Network, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/IPDN#NASDAQ">IPDN</a>) rose 21.7% to $2.30 in pre-market trading.</li>
<li>Wellchange Holdings Company Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/WCT#NASDAQ">WCT</a>) gained 16% to $0.3248 in pre-market trading after jumping 44% on Friday.</li>
<li>Baosheng Media Group Holdings Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BAOS#NASDAQ">BAOS</a>) gained 15.3% to $1.96 in pre-market after falling 14% on Friday.</li>
<li>Maze Therapeutics, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MAZE#NASDAQ">MAZE</a>) rose 9.2% to $9.90 in pre-market trading.</li>
<li>Ekso Bionics Holdings, Inc.  (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/EKSO#NASDAQ">EKSO</a>) gained 8.1% to $0.4087 in pre-market trading following a 10% decline on Friday.</li>
<li>Ternium S.A. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TX#NYSE">TX</a>) rose 7.7% to $30.38 in pre-market trading after falling 5% on Friday.</li>
</ul>
<h3 class="wp-block-heading">Losers</h3>
<ul>
<li>BrightSpring Health Services, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BTSG#NASDAQ">BTSG</a>) fell 35.8% to $11.01 in pre-market trading.</li>
<li>American Rebel Holdings, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AREB#NASDAQ">AREB</a>) shares tumbled 30.3% to $13.54 in pre-market trading after jumping 392% on Friday. The company, on Friday, announced up to $11 million private placement priced at-the-market under Nasdaq rules.</li>
<li>BTCS Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BTCS#NASDAQ">BTCS</a>) fell 29.3% to $1.03 in today's pre-market trading after declining 4% in Friday.</li>
<li>CECO Environmental Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CECO#NASDAQ">CECO</a>) shares dipped 29.3% to $14.00 in pre-market trading.</li>
<li>Potbelly Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PBPB#NASDAQ">PBPB</a>) fell 28.6% to $6.30 in pre-market trading after dipping 6% on Friday.</li>
<li>SandRidge Energy, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SD#NYSE">SD</a>) shares fell 26.3% to $7.10 in pre-market trading after dipping 9% on Friday.</li>
<li>PLDT Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/PHI#NYSE">PHI</a>) shares fell 14.7% to $18.10 in pre-market trading following a 4% decline on Friday.</li>
<li>First National Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FXNC#NASDAQ">FXNC</a>) fell 13.8% to $17.11 in pre-market trading.</li>
<li>Smith Douglas Homes Corp. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SDHC#NYSE">SDHC</a>) declined 13% to $17.01 in pre-market trading after gaining 5% on Friday.</li>
<li>USCB Financial Holdings, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/USCB#NASDAQ">USCB</a>) dipped 7.1% to $15.79 in pre-market trading. USCB Financial Holdings will report financial results for the quarter ended March 31, after the market closes on Thursday, April 24.</li>
</ul>
Now Read This: 
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<li><a href="https://www.benzinga.com/analyst-ratings/price-target/25/04/44645517/wall-streets-most-accurate-analysts-give-their-take-on-3-health-care-stocks-with-over-4-dividend-yields-2">Wall Street&#8217;s Most Accurate Analysts Give Their Take On 3 Health Care Stocks With Over 4% Dividend Yields</a> </li>
</ul>
Photo via Shutterstock

Pre-Market Outlook

AREB

BAOS

BJDX

BTCS

BTSG

CECO

CHSN

DEVS

EKSO

FXNC

IPDN

MAZE

PBPB

SDHC

SUNE

USCB

Why Chanson International Holding Shares Are Trading Higher By Around 170%; Here Are 20 Stocks Moving Premarket

Beneficient (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BENF#NASDAQ">BENF</a>) ("Ben" or the "Company"), a technology-enabled platform providing exit opportunities and primary capital solutions and related trust and custody services to holders of alternative assets through its proprietary online platform AltAccess, today announced it has closed on the financing of a $9.6 million primary capital commitment for Pulse Pioneer Fund, LP ("Fund"), a fund managed by Pulse Pioneer GP, LLC, an asset manager that manages venture capital funds that invest in scalable climate companies within its target interdependent investment verticals. The transaction represents Ben's first GP Primary transaction of the fiscal year. In exchange for an interest in the Fund, the Fund received approximately $9.6 million in stated value of shares of the Company's Resettable Convertible Preferred Stock (the "Preferred Stock"), which is convertible at the election of the holder into shares of the Company's Class A common stock, subject to the terms and conditions of the transaction documents. As a result of the transaction, the collateral for Company's ExAlt loan portfolio is expected to increase by approximately $9.6 million of interests in alternative assets.

BENF

Beneficient Backs Venture Fund With $9.6M in Preferred Stock for Climate Investments

Macro Economic Events

Reuters Reported Italy's Foreign Minister Suggested EU Could Postpone Initial Counter-Tariffs Against U.S. To April 30 From April 15

<ul>
<li>Participants with abnormal left ventricular mass index (LVMI) at baseline achieved 25% mean reduction in LVMI by 12 months or sooner</li>
<li>Clinically meaningful improvements in majority of participants across cardiac biomarkers and functional measures</li>
<li>All SUNRISE-FA participants achieved meaningful increases in frataxin expression at 3-months post treatment; 115% average cardiac frataxin expression increase in high dose cohort, demonstrating dose response</li>
<li>Frataxin expression and LVMI improvement exceed co-primary target thresholds for planned registrational study</li>
<li>LX2006 generally well tolerated with no signs of complement activation or other immunogenicity to date</li>
</ul>

Biotech

Health Care

LXEO

Lexeo Therapeutics Announced Interim Data Across All Dose Cohorts Of LX2006 For Friedreich Ataxia Cardiomyopathy. In Both Lexeo-sponsored SUNRISE-FA Phase 1/2 Trial And The Weill Cornell Medicine Investigator-Initiated Phase 1A Trial, LX2006 Showed Clinically Significant Improvements In Cardiac Biomarkers And Functional Measures, And Increased Frataxin Protein Expression Was Observed In All Participants With Cardiac Biopsies

OS Therapies (NYSE-A: OSTX) ("OS Therapies" or "the Company"), a clinical-stage immunotherapy and Antibody Drug Conjugate (ADC) biopharmaceutical company, today announced that it has submitted a request for a formal meeting with the Center for Biologics Evaluation and Research (CBER) of the United States Food &amp; Drug Administration (FDA) to gain alignment on the clinical endpoints required to support Breakthrough Therapy Designation (BTD) and Accelerated Approval via a conditional BLA of investigational off-the-shelf immunotherapy candidate OST-HER2 in the prevention or delay of recurrence of fully resected, lung metastatic osteosarcoma. The meeting is expected to occur in the second quarter of 2025, and thereafter the Company intends to initiate a rolling BLA submission with the potential to receive Accelerated Approval as early as year-end 2025. The Company has sufficient cash on hand to operate into mid-2026.

OSTX

OS Therapies Seeks FDA Breakthrough Tag for Osteosarcoma Drug, Eyes 2025 Approval

The apparel industry is bracing for a significant impact as tariffs are set to increase the cost of clothing, potentially ending the era of cheap garments.
What Happened: The Trump administration&#8217;s tariffs are poised to hit the clothing industry particularly hard<a href="https://www.marketplace.org/2025/04/04/tariffs-could-bring-an-end-to-the-days-of-cheap-clothing/">, reported</a> Marketplace on Monday. The majority of clothes and shoes purchased in the U.S. are imported, with a significant portion coming from Southeast Asian countries. These imports are soon to be subject to tariffs exceeding 30%.
When President Trump increased&nbsp;taxes on imports from China&nbsp;during his first term, many apparel companies shifted their operations, particularly to Vietnam, as noted by David Swartz of Morningstar. However, with the new&nbsp;tariffs targeting all U.S. trading&nbsp;partners, companies have no place to escape. &#8220;They&nbsp;cannot move production to other&nbsp;countries to avoid a tariff&nbsp;in one country in any&nbsp;realistic time frame,&#8221; Swartz said.
See Also:&nbsp;<a href="https://benzinga.com/general/market-summary/25/04/44660779/sp-500-dow-jones-on-course-to-mimic-rare-consecutive-losses-not-seen-since-the-great-depre" target="_blank" rel="noreferrer noopener">S&amp;P 500, Dow Jones On Course To Mimic Rare Consecutive Losses Not Seen Since The Great Depression: What&#8217;s Driving the Fear?</a>
Stephen Lamar, head of the American Apparel and Footwear Association, ruled out the possibility of moving garment manufacturing to the U.S., citing a lack of labor, skill sets, infrastructure, and capabilities to scale up production. Denise Green at Cornell University added, &#8220;We&#8217;re not going to be able to buy clothing as inexpensively as we have in the past.&#8221;
Why It Matters: <a href="https://in.benzinga.com/markets/25/04/44656680/trumps-10-tariff-on-most-imports-is-finally-here-taking-effect-saturday">The new tariffs</a>, part of President Trump&#8217;s strategy to stimulate domestic investment by companies seeking to evade import taxes, have sparked a significant market reaction, escalating U.S. duties to their highest level in over a century.
The tariffs have stirred global markets, leading to a <a href="https://in.benzinga.com/media/25/04/44657800/trumps-tariffs-stir-global-markets-wall-street-loses-2-trillion-and-more-this-week-in-economics">loss of $2 trillion</a> on Wall Street. <a href="https://in.benzinga.com/25/04/44660475/more-than-50-nations-ready-to-revisit-tariffs-says-white-house-advisor">Over 50 countries</a>, targets of reciprocal tariffs by the U.S., have since reached out to begin negotiations on the high import tariffs, according to the White House. 
Read Next:
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<li><a href="https://www.benzinga.com/tech/25/04/44658417/warren-buffett-stands-tall-in-2025-as-elon-musk-jeff-bezos-and-mark-zuckerberg-bleed-billions-in-net-worth-oracle-of-omaha-emerges-as-lone-gainer-among-top-billionaires-amid-market-rout" target="_blank" rel="noreferrer noopener">Warren Buffett Stands Tall In 2025 As Elon Musk, Jeff Bezos And Mark Zuckerberg Bleed Billions In Net Worth: ‘Oracle Of Omaha&#8217; Emerges As Lone Gainer Among Top Billionaires Amid Market Rout</a></li>
</ul>
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Press Releases

AN2 Therapeutics Adopts Limited Duration Stockholder Rights Plan

AN2 Therapeutics to Present at the H.C. Wainwright 26th Annual Global Investment Conference

AN2 Therapeutics Receives Continuation Grant to Discover Novel Boron Based Therapies for Tuberculosis (caused by Mycobacterium tuberculosis) and Malaria

AN2 Therapeutics Reports Third Quarter 2024 Financial Results, Provides Important EBO-301 Update and Highlights Progress Across Boron Chemistry Pipeline

AN2 Therapeutics to Participate at Upcoming Investor Conferences

AN2 Therapeutics to Present at the Oppenheimer 35th Annual Healthcare Life Sciences Conference

AN2 Provides Strategic Update for Phase 3 EBO-301 Trial in Treatment Refractory MAC Lung Disease

AN2 Therapeutics to Present at Leerink Partners Global Healthcare Conference

AN2 Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business and Scientific Highlights

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