La vendita allo scoperto per Panbela Therapeutics dà agli investitori un'idea del grado in cui gli investitori stanno scommettendo sul declino delle azioni di Panbela Therapeutics. I dati relativi alle vendite allo scoperto vengono aggiornati ogni due settimane.

Panbela Therapeutics (OTC:PBLA) Azioni, Report sulle vendite allo scoperto

Panbela Therapeutics

Panbela Therapeutics Inc is a clinical-stage biopharmaceutical company developing disruptive therapeutics for the treatment of patients with urgent unmet medical needs. The Company's pipeline assets are ivospemin (SBP-101), FlynpoviTM (eflornithine (CPP-1X) and sulindac), and eflornithine (CPP-1X), which provide a multi-targeted approach to reset dysregulated biology present in many types of diseases such as cancer and autoimmunity.

<a href="https://www.fda.gov/drugs/development-resources/reviews-pediatric-studies-conducted-under-bpca-and-pediatric-assessments-conducted-under-prea-2012" title="https://www.fda.gov/drugs/development-resources/reviews-pediatric-studies-conducted-under-bpca-and-pediatric-assessments-conducted-under-prea-2012">https://www.fda.gov/drugs/development-resources/reviews-pediatric-studies-conducted-under-bpca-and-pediatric-assessments-conducted-under-prea-2012</a>

Biotech

News

General

FDA Announces Manufacture Of Novo Nordisks's Tresiba Injection, 3 ML Insulin Degludec 100 Units/ML , 200 Units/ML To Be Discontinued From Dec 31; Manufacture Of Novo Nordisks's Tresiba, Injection, 10 ML Insulin Degludec Vial To Be Discontinued From Dec 31

LUCID CAPITAL MARKETS analyst Christopher Liu initiates coverage on Genelux (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GNLX#NASDAQ">GNLX</a>) with a Buy rating and announces Price Target of $10.

Price Target

Initiation

Analyst Ratings

GNLX

LUCID CAPITAL MARKETS Initiates Coverage On Genelux with Buy Rating, Announces Price Target of $10

This whale alert can help traders discover the next big trading opportunities.
Whales are entities with large sums of money and we track their transactions here at Benzinga on our options activity scanner.
Traders will search for circumstances when the market estimation of an option diverges heavily from its normal worth. High amounts of trading activity could push option prices to exaggerated or underestimated levels. 
Here's the list of options activity happening in today's session: 
<table>
<thead>
<tr>
<th>Symbol</th>
<th>PUT/CALL</th>
<th>Trade Type</th>
<th>Sentiment</th>
<th>Exp. Date</th>
<th>Strike Price</th>
<th>Total Trade Price</th>
<th>Open Interest</th>
<th>Volume</th>
</tr>
</thead>
<tbody>
<tr>
<td>HOOD</td>
<td>CALL</td>
<td>TRADE</td>
<td>BULLISH</td>
<td>01/16/26</td>
<td>$100.00</td>
<td>$72.7K</td>
<td>18.7K</td>
<td>4.6K</td>
</tr>
<tr>
<td>COIN</td>
<td>PUT</td>
<td>SWEEP</td>
<td>NEUTRAL</td>
<td>07/25/25</td>
<td>$420.00</td>
<td>$57.6K</td>
<td>783</td>
<td>3.9K</td>
</tr>
<tr>
<td>BAC</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>09/19/25</td>
<td>$50.00</td>
<td>$73.1K</td>
<td>16.9K</td>
<td>3.6K</td>
</tr>
<tr>
<td>XYZ</td>
<td>CALL</td>
<td>TRADE</td>
<td>NEUTRAL</td>
<td>08/01/25</td>
<td>$80.00</td>
<td>$25.5K</td>
<td>1.0K</td>
<td>3.6K</td>
</tr>
<tr>
<td>GLXY</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>07/25/25</td>
<td>$30.00</td>
<td>$29.9K</td>
<td>3.2K</td>
<td>2.4K</td>
</tr>
<tr>
<td>PAGS</td>
<td>PUT</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>01/16/26</td>
<td>$8.00</td>
<td>$72.0K</td>
<td>1.2K</td>
<td>1.8K</td>
</tr>
<tr>
<td>RKT</td>
<td>CALL</td>
<td>TRADE</td>
<td>BULLISH</td>
<td>09/19/25</td>
<td>$15.20</td>
<td>$32.2K</td>
<td>6.3K</td>
<td>1.4K</td>
</tr>
<tr>
<td>CIA</td>
<td>PUT</td>
<td>SWEEP</td>
<td>NEUTRAL</td>
<td>11/21/25</td>
<td>$5.00</td>
<td>$27.9K</td>
<td>10.4K</td>
<td>1.3K</td>
</tr>
<tr>
<td>TFC</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>08/15/25</td>
<td>$46.50</td>
<td>$56.4K</td>
<td>0</td>
<td>1.3K</td>
</tr>
<tr>
<td>BULL</td>
<td>CALL</td>
<td>TRADE</td>
<td>BULLISH</td>
<td>08/15/25</td>
<td>$14.00</td>
<td>$49.2K</td>
<td>0</td>
<td>273</td>
</tr>
</tbody>
</table>

<h2>Explanation</h2>
These bullet-by-bullet explanations have been constructed using the accompanying table. 
• Regarding HOOD (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HOOD#NASDAQ">HOOD</a>), we observe a call option trade with bullish sentiment. It expires in 179 day(s) on January 16, 2026. Parties traded 30 contract(s) at a $100.00 strike. The total cost received by the writing party (or parties) was $72.7K, with a price of $2425.0 per contract. There were 18738 open contracts at this strike prior to today, and today 4605 contract(s) were bought and sold. 
• For COIN (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/COIN#NASDAQ">COIN</a>), we notice a put option sweep that happens to be neutral, expiring in 4 day(s) on July 25, 2025. This event was a transfer of 69 contract(s) at a $420.00 strike. This particular put needed to be split into 8 different trades to become filled. The total cost received by the writing party (or parties) was $57.6K, with a price of $838.0 per contract. There were 783 open contracts at this strike prior to today, and today 3950 contract(s) were bought and sold. 
• For BAC (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BAC#NYSE">BAC</a>), we notice a call option sweep that happens to be bullish, expiring in 60 day(s) on September 19, 2025. This event was a transfer of 1000 contract(s) at a $50.00 strike. This particular call needed to be split into 36 different trades to become filled. The total cost received by the writing party (or parties) was $73.1K, with a price of $73.0 per contract. There were 16952 open contracts at this strike prior to today, and today 3685 contract(s) were bought and sold. 
• For XYZ (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/XYZ#NYSE">XYZ</a>), we notice a call option trade that happens to be neutral, expiring in 11 day(s) on August 1, 2025. This event was a transfer of 139 contract(s) at a $80.00 strike. The total cost received by the writing party (or parties) was $25.5K, with a price of $184.0 per contract. There were 1098 open contracts at this strike prior to today, and today 3652 contract(s) were bought and sold. 
• For GLXY (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GLXY#NASDAQ">GLXY</a>), we notice a call option sweep that happens to be bullish, expiring in 4 day(s) on July 25, 2025. This event was a transfer of 200 contract(s) at a $30.00 strike. This particular call needed to be split into 7 different trades to become filled. The total cost received by the writing party (or parties) was $29.9K, with a price of $149.0 per contract. There were 3296 open contracts at this strike prior to today, and today 2447 contract(s) were bought and sold. 
• For PAGS (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/PAGS#NYSE">PAGS</a>), we notice a put option sweep that happens to be bullish, expiring in 179 day(s) on January 16, 2026. This event was a transfer of 800 contract(s) at a $8.00 strike. This particular put needed to be split into 7 different trades to become filled. The total cost received by the writing party (or parties) was $72.0K, with a price of $90.0 per contract. There were 1253 open contracts at this strike prior to today, and today 1840 contract(s) were bought and sold. 
• For RKT (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/RKT#NYSE">RKT</a>), we notice a call option trade that happens to be bullish, expiring in 60 day(s) on September 19, 2025. This event was a transfer of 200 contract(s) at a $15.20 strike. The total cost received by the writing party (or parties) was $32.2K, with a price of $161.0 per contract. There were 6307 open contracts at this strike prior to today, and today 1425 contract(s) were bought and sold. 
• For CIA (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CIA#NYSE">CIA</a>), we notice a put option sweep that happens to be neutral, expiring in 123 day(s) on November 21, 2025. This event was a transfer of 150 contract(s) at a $5.00 strike. This particular put needed to be split into 9 different trades to become filled. The total cost received by the writing party (or parties) was $27.9K, with a price of $187.0 per contract. There were 10400 open contracts at this strike prior to today, and today 1370 contract(s) were bought and sold. 
• For TFC (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TFC#NYSE">TFC</a>), we notice a call option sweep that happens to be bullish, expiring in 25 day(s) on August 15, 2025. This event was a transfer of 1341 contract(s) at a $46.50 strike. This particular call needed to be split into 72 different trades to become filled. The total cost received by the writing party (or parties) was $56.4K, with a price of $42.0 per contract. There were 0 open contracts at this strike prior to today, and today 1342 contract(s) were bought and sold. 
• Regarding BULL (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BULL#NASDAQ">BULL</a>), we observe a call option trade with bullish sentiment. It expires in 25 day(s) on August 15, 2025. Parties traded 200 contract(s) at a $14.00 strike. The total cost received by the writing party (or parties) was $49.2K, with a price of $246.0 per contract. There were 0 open contracts at this strike prior to today, and today 273 contract(s) were bought and sold. 
Options Alert Terminology 
 - Call Contracts: The right to buy shares as indicated in the contract. 
 - Put Contracts: The right to sell shares as indicated in the contract. 
 - Expiration Date: When the contract expires. One must act on the contract by this date if one wants to use it. 
 - Premium/Option Price: The price of the contract. 
For more information, visit our <a href="https://pro.benzinga.com/blog/how-to-understand-option-alerts/">Guide to Understanding Options Alerts</a> or read <a href="https://www.benzinga.com/markets/options">more news on unusual options activity</a>. 
This article was generated by Benzinga's automated content engine and reviewed by an editor.

Options

BULL

COIN

GLXY

HOOD

PAGS

10 Financials Stocks With Whale Alerts In Today's Session

This whale alert can help traders discover the next big trading opportunities.
Whales are entities with large sums of money and we track their transactions here at Benzinga on our options activity scanner.
Traders will search for circumstances when the market estimation of an option diverges heavily from its normal worth. High amounts of trading activity could push option prices to exaggerated or underestimated levels. 
Here's the list of options activity happening in today's session: 
<table>
<thead>
<tr>
<th>Symbol</th>
<th>PUT/CALL</th>
<th>Trade Type</th>
<th>Sentiment</th>
<th>Exp. Date</th>
<th>Strike Price</th>
<th>Total Trade Price</th>
<th>Open Interest</th>
<th>Volume</th>
</tr>
</thead>
<tbody>
<tr>
<td>AMZN</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>07/25/25</td>
<td>$230.00</td>
<td>$41.0K</td>
<td>23.4K</td>
<td>40.5K</td>
</tr>
<tr>
<td>PDD</td>
<td>PUT</td>
<td>TRADE</td>
<td>BEARISH</td>
<td>01/16/26</td>
<td>$110.00</td>
<td>$34.3K</td>
<td>5.2K</td>
<td>6.0K</td>
</tr>
<tr>
<td>QS</td>
<td>CALL</td>
<td>TRADE</td>
<td>BEARISH</td>
<td>07/25/25</td>
<td>$10.00</td>
<td>$292.0K</td>
<td>2.0K</td>
<td>4.2K</td>
</tr>
<tr>
<td>BABA</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>09/19/25</td>
<td>$125.00</td>
<td>$66.9K</td>
<td>12.0K</td>
<td>1.9K</td>
</tr>
<tr>
<td>YUMC</td>
<td>CALL</td>
<td>TRADE</td>
<td>BULLISH</td>
<td>01/16/26</td>
<td>$47.50</td>
<td>$528.0K</td>
<td>5.2K</td>
<td>1.2K</td>
</tr>
<tr>
<td>GM</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>07/25/25</td>
<td>$54.00</td>
<td>$28.4K</td>
<td>2.3K</td>
<td>1.0K</td>
</tr>
<tr>
<td>JD</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>09/19/25</td>
<td>$33.00</td>
<td>$27.5K</td>
<td>4.6K</td>
<td>907</td>
</tr>
<tr>
<td>SG</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>01/15/27</td>
<td>$15.00</td>
<td>$25.8K</td>
<td>1.4K</td>
<td>321</td>
</tr>
<tr>
<td>SBET</td>
<td>CALL</td>
<td>TRADE</td>
<td>BULLISH</td>
<td>08/22/25</td>
<td>$50.00</td>
<td>$53.4K</td>
<td>1</td>
<td>315</td>
</tr>
<tr>
<td>JACK</td>
<td>PUT</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>10/17/25</td>
<td>$22.50</td>
<td>$90.8K</td>
<td>379</td>
<td>284</td>
</tr>
</tbody>
</table>

<h2>Explanation</h2>
These itemized elaborations have been created using the accompanying table. 
• For AMZN (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMZN#NASDAQ">AMZN</a>), we notice a call option sweep that happens to be bullish, expiring in 4 day(s) on July 25, 2025. This event was a transfer of 200 contract(s) at a $230.00 strike. This particular call needed to be split into 12 different trades to become filled. The total cost received by the writing party (or parties) was $41.0K, with a price of $205.0 per contract. There were 23491 open contracts at this strike prior to today, and today 40584 contract(s) were bought and sold. 
• For PDD (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PDD#NASDAQ">PDD</a>), we notice a put option trade that happens to be bearish, expiring in 179 day(s) on January 16, 2026. This event was a transfer of 33 contract(s) at a $110.00 strike. The total cost received by the writing party (or parties) was $34.3K, with a price of $1040.0 per contract. There were 5251 open contracts at this strike prior to today, and today 6073 contract(s) were bought and sold. 
• Regarding QS (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/QS#NYSE">QS</a>), we observe a call option trade with bearish sentiment. It expires in 4 day(s) on July 25, 2025. Parties traded 1000 contract(s) at a $10.00 strike. The total cost received by the writing party (or parties) was $292.0K, with a price of $292.0 per contract. There were 2038 open contracts at this strike prior to today, and today 4244 contract(s) were bought and sold. 
• Regarding BABA (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BABA#NYSE">BABA</a>), we observe a call option sweep with bullish sentiment. It expires in 60 day(s) on September 19, 2025. Parties traded 100 contract(s) at a $125.00 strike. This particular call needed to be split into 7 different trades to become filled. The total cost received by the writing party (or parties) was $66.9K, with a price of $667.0 per contract. There were 12098 open contracts at this strike prior to today, and today 1969 contract(s) were bought and sold. 
• Regarding YUMC (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/YUMC#NYSE">YUMC</a>), we observe a call option trade with bullish sentiment. It expires in 179 day(s) on January 16, 2026. Parties traded 1200 contract(s) at a $47.50 strike. The total cost received by the writing party (or parties) was $528.0K, with a price of $440.0 per contract. There were 5215 open contracts at this strike prior to today, and today 1200 contract(s) were bought and sold. 
• For GM (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GM#NYSE">GM</a>), we notice a call option sweep that happens to be bullish, expiring in 4 day(s) on July 25, 2025. This event was a transfer of 200 contract(s) at a $54.00 strike. This particular call needed to be split into 9 different trades to become filled. The total cost received by the writing party (or parties) was $28.4K, with a price of $142.0 per contract. There were 2327 open contracts at this strike prior to today, and today 1019 contract(s) were bought and sold. 
• For JD (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/JD#NASDAQ">JD</a>), we notice a call option sweep that happens to be bullish, expiring in 60 day(s) on September 19, 2025. This event was a transfer of 100 contract(s) at a $33.00 strike. This particular call needed to be split into 22 different trades to become filled. The total cost received by the writing party (or parties) was $27.5K, with a price of $275.0 per contract. There were 4652 open contracts at this strike prior to today, and today 907 contract(s) were bought and sold. 
• Regarding SG (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SG#NYSE">SG</a>), we observe a call option sweep with bullish sentiment. It expires in 543 day(s) on January 15, 2027. Parties traded 50 contract(s) at a $15.00 strike. This particular call needed to be split into 3 different trades to become filled. The total cost received by the writing party (or parties) was $25.8K, with a price of $518.0 per contract. There were 1461 open contracts at this strike prior to today, and today 321 contract(s) were bought and sold. 
• Regarding SBET (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SBET#NASDAQ">SBET</a>), we observe a call option trade with bullish sentiment. It expires in 32 day(s) on August 22, 2025. Parties traded 300 contract(s) at a $50.00 strike. The total cost received by the writing party (or parties) was $53.4K, with a price of $178.0 per contract. There were 1 open contracts at this strike prior to today, and today 315 contract(s) were bought and sold. 
• For JACK (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/JACK#NASDAQ">JACK</a>), we notice a put option sweep that happens to be bearish, expiring in 88 day(s) on October 17, 2025. This event was a transfer of 284 contract(s) at a $22.50 strike. This particular put needed to be split into 5 different trades to become filled. The total cost received by the writing party (or parties) was $90.8K, with a price of $320.0 per contract. There were 379 open contracts at this strike prior to today, and today 284 contract(s) were bought and sold. 
Options Alert Terminology 
 - Call Contracts: The right to buy shares as indicated in the contract. 
 - Put Contracts: The right to sell shares as indicated in the contract. 
 - Expiration Date: When the contract expires. One must act on the contract by this date if one wants to use it. 
 - Premium/Option Price: The price of the contract. 
For more information, visit our <a href="https://pro.benzinga.com/blog/how-to-understand-option-alerts/">Guide to Understanding Options Alerts</a> or read <a href="https://www.benzinga.com/markets/options">more about unusual options activity</a>. 
This article was generated by Benzinga's automated content engine and reviewed by an editor.

AMZN

BABA

JACK

Citigourp Global Markets 2% Protected Notes Linked To The Djia

SBET

YUMC

10 Consumer Discretionary Stocks Whale Activity In Today's Session

This whale alert can help traders discover the next big trading opportunities.
Whales are entities with large sums of money and we track their transactions here at Benzinga on our options activity scanner.
Traders will search for circumstances when the market estimation of an option diverges heavily from its normal worth. High amounts of trading activity could push option prices to exaggerated or underestimated levels. 
Below are some instances of options activity happening in the Information Technology sector: 
<table>
<thead>
<tr>
<th>Symbol</th>
<th>PUT/CALL</th>
<th>Trade Type</th>
<th>Sentiment</th>
<th>Exp. Date</th>
<th>Strike Price</th>
<th>Total Trade Price</th>
<th>Open Interest</th>
<th>Volume</th>
</tr>
</thead>
<tbody>
<tr>
<td>NVDA</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>07/25/25</td>
<td>$172.50</td>
<td>$63.4K</td>
<td>28.5K</td>
<td>71.3K</td>
</tr>
<tr>
<td>AMD</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>07/25/25</td>
<td>$160.00</td>
<td>$25.4K</td>
<td>19.5K</td>
<td>42.3K</td>
</tr>
<tr>
<td>INTC</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>08/15/25</td>
<td>$26.00</td>
<td>$39.2K</td>
<td>24.0K</td>
<td>2.9K</td>
</tr>
<tr>
<td>MSFT</td>
<td>CALL</td>
<td>TRADE</td>
<td>BEARISH</td>
<td>01/16/26</td>
<td>$575.00</td>
<td>$1.6 million</td>
<td>417</td>
<td>1.5K</td>
</tr>
<tr>
<td>U</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>11/21/25</td>
<td>$25.00</td>
<td>$38.3K</td>
<td>3.7K</td>
<td>1.4K</td>
</tr>
<tr>
<td>MCHP</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BULLISH</td>
<td>07/25/25</td>
<td>$72.00</td>
<td>$66.0K</td>
<td>75</td>
<td>1.2K</td>
</tr>
<tr>
<td>CRWV</td>
<td>CALL</td>
<td>TRADE</td>
<td>NEUTRAL</td>
<td>09/19/25</td>
<td>$160.00</td>
<td>$27.8K</td>
<td>6.7K</td>
<td>1.1K</td>
</tr>
<tr>
<td>CLSK</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>09/19/25</td>
<td>$18.00</td>
<td>$50.0K</td>
<td>2.4K</td>
<td>1.0K</td>
</tr>
<tr>
<td>CVLT</td>
<td>PUT</td>
<td>TRADE</td>
<td>BEARISH</td>
<td>08/15/25</td>
<td>$160.00</td>
<td>$28.7K</td>
<td>149</td>
<td>1.0K</td>
</tr>
<tr>
<td>QUBT</td>
<td>CALL</td>
<td>SWEEP</td>
<td>BEARISH</td>
<td>08/15/25</td>
<td>$19.00</td>
<td>$28.5K</td>
<td>2.2K</td>
<td>793</td>
</tr>
</tbody>
</table>

<h2>Explanation</h2>
These bullet-by-bullet explanations have been constructed using the accompanying table. 
• For NVDA (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVDA#NASDAQ">NVDA</a>), we notice a call option sweep that happens to be bullish, expiring in 4 day(s) on July 25, 2025. This event was a transfer of 247 contract(s) at a $172.50 strike. This particular call needed to be split into 7 different trades to become filled. The total cost received by the writing party (or parties) was $63.4K, with a price of $257.0 per contract. There were 28536 open contracts at this strike prior to today, and today 71326 contract(s) were bought and sold. 
• For AMD (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMD#NASDAQ">AMD</a>), we notice a call option sweep that happens to be bearish, expiring in 4 day(s) on July 25, 2025. This event was a transfer of 100 contract(s) at a $160.00 strike. This particular call needed to be split into 4 different trades to become filled. The total cost received by the writing party (or parties) was $25.4K, with a price of $254.0 per contract. There were 19512 open contracts at this strike prior to today, and today 42314 contract(s) were bought and sold. 
• For INTC (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/INTC#NASDAQ">INTC</a>), we notice a call option sweep that happens to be bullish, expiring in 25 day(s) on August 15, 2025. This event was a transfer of 800 contract(s) at a $26.00 strike. This particular call needed to be split into 26 different trades to become filled. The total cost received by the writing party (or parties) was $39.2K, with a price of $49.0 per contract. There were 24050 open contracts at this strike prior to today, and today 2990 contract(s) were bought and sold. 
• Regarding MSFT (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MSFT#NASDAQ">MSFT</a>), we observe a call option trade with bearish sentiment. It expires in 179 day(s) on January 16, 2026. Parties traded 1500 contract(s) at a $575.00 strike. The total cost received by the writing party (or parties) was $1.6 million, with a price of $1072.0 per contract. There were 417 open contracts at this strike prior to today, and today 1502 contract(s) were bought and sold. 
• For U (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/U#NYSE">U</a>), we notice a call option sweep that happens to be bearish, expiring in 123 day(s) on November 21, 2025. This event was a transfer of 30 contract(s) at a $25.00 strike. This particular call needed to be split into 4 different trades to become filled. The total cost received by the writing party (or parties) was $38.3K, with a price of $1278.0 per contract. There were 3794 open contracts at this strike prior to today, and today 1490 contract(s) were bought and sold. 
• For MCHP (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MCHP#NASDAQ">MCHP</a>), we notice a call option sweep that happens to be bullish, expiring in 4 day(s) on July 25, 2025. This event was a transfer of 200 contract(s) at a $72.00 strike. This particular call needed to be split into 3 different trades to become filled. The total cost received by the writing party (or parties) was $66.0K, with a price of $330.0 per contract. There were 75 open contracts at this strike prior to today, and today 1296 contract(s) were bought and sold. 
• Regarding CRWV (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CRWV#NASDAQ">CRWV</a>), we observe a call option trade with neutral sentiment. It expires in 60 day(s) on September 19, 2025. Parties traded 65 contract(s) at a $160.00 strike. The total cost received by the writing party (or parties) was $27.8K, with a price of $428.0 per contract. There were 6708 open contracts at this strike prior to today, and today 1151 contract(s) were bought and sold. 
• For CLSK (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CLSK#NASDAQ">CLSK</a>), we notice a call option sweep that happens to be bearish, expiring in 60 day(s) on September 19, 2025. This event was a transfer of 1000 contract(s) at a $18.00 strike. This particular call needed to be split into 19 different trades to become filled. The total cost received by the writing party (or parties) was $50.0K, with a price of $50.0 per contract. There were 2411 open contracts at this strike prior to today, and today 1064 contract(s) were bought and sold. 
• For CVLT (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CVLT#NASDAQ">CVLT</a>), we notice a put option trade that happens to be bearish, expiring in 25 day(s) on August 15, 2025. This event was a transfer of 41 contract(s) at a $160.00 strike. The total cost received by the writing party (or parties) was $28.7K, with a price of $700.0 per contract. There were 149 open contracts at this strike prior to today, and today 1048 contract(s) were bought and sold. 
• Regarding QUBT (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/QUBT#NASDAQ">QUBT</a>), we observe a call option sweep with bearish sentiment. It expires in 25 day(s) on August 15, 2025. Parties traded 136 contract(s) at a $19.00 strike. This particular call needed to be split into 3 different trades to become filled. The total cost received by the writing party (or parties) was $28.5K, with a price of $210.0 per contract. There were 2277 open contracts at this strike prior to today, and today 793 contract(s) were bought and sold. 
Options Alert Terminology 
 - Call Contracts: The right to buy shares as indicated in the contract. 
 - Put Contracts: The right to sell shares as indicated in the contract. 
 - Expiration Date: When the contract expires. One must act on the contract by this date if one wants to use it. 
 - Premium/Option Price: The price of the contract. 
For more information, visit our <a href="https://pro.benzinga.com/blog/how-to-understand-option-alerts/">Guide to Understanding Options Alerts</a> or read <a href="https://www.benzinga.com/markets/options">more news on unusual options activity</a>. 
This article was generated by Benzinga's automated content engine and reviewed by an editor.

CLSK

CRWV

CVLT

INTC

MCHP

MSFT

NVDA

QUBT

10 Information Technology Stocks With Whale Alerts In Today's Session

CenterPoint Energy today announced that Jesus Soto, Jr, a well-respected, energy industry executive with deep Texas roots will join the company as Executive Vice President and Chief Operating Officer. Soto will oversee the company's Electric Operations, Gas Operations, Safety, Supply Chain, and Customer Care functions, across all the states that CenterPoint serves. He will join the company on Aug. 11, 2025, and report to President &amp; CEO Jason Wells.

Management

CenterPoint Energy Appoints Jesus Soto Jr As EVP And COO, Effective Aug. 11, 2025

Alkermes plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ALKS#NASDAQ">ALKS</a>) on Monday released topline results from the randomized double-blind treatment period of the Vibrance-1 phase 2 study evaluating alixorexton in patients <a target="_blank" href="https://www.benzinga.com/general/biotech" rel="noreferrer noopener">with narcolepsy type 1 (NT1)</a>.
Narcolepsy is a chronic neurological disorder that disrupts the body&#8217;s ability to regulate sleep-wake cycles. It&#8217;s characterized by excessive daytime sleepiness and sudden, uncontrollable sleep attacks.
Alixorexton, formerly ALKS 2680, is an investigational, oral orexin 2 receptor (OX2R) agonist in phase 2 development as a once-daily treatment for NT1, narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH).
Also Read: <a target="_blank" href="https://www.benzinga.com/25/02/43826737/harmony-biosciences-stock-falls-on-fda-setback-for-pitolisant-in-sleeping-disorder" rel="noreferrer noopener">Harmony Biosciences Stock Falls On FDA Setback For Pitolisant In Sleeping Disorder</a>
In Vibrance-1, alixorexton met the primary endpoint across all doses tested, demonstrating statistically significant, clinically meaningful, and dose-dependent improvements in wakefulness on the Maintenance of Wakefulness Test (MWT) from <a target="_blank" href="https://www.benzinga.com/pressreleases/25/07/n46513802/alkermes-announces-positive-topline-results-from-vibrance-1-phase-2-study-of-once-daily-alixorexto" rel="noreferrer noopener">baseline compared to placebo</a>.
In addition to achieving normative wakefulness across all dose groups on the MWT (mean sleep latency >20 minutes), once-daily alixorexton demonstrated robust and clinically meaningful improvements compared to placebo on patient-reported outcomes related to excessive daytime sleepiness and other key symptoms such as fatigue and cognition. 
Alixorexton was generally well tolerated at all doses tested. These data support rapid initiation of a global phase 3 program of alixorexton in patients with NT1.
<h2 class="wp-block-heading">Key Secondary Endpoints</h2>
Epworth Sleepiness Scale (ESS): At all doses tested, alixorexton drove statistically significant and clinically meaningful improvements from baseline in excessive daytime sleepiness compared to placebo on the Epworth Sleepiness Scale at week six (p&lt;0.0001 at all doses).
Weekly Cataplexy Rates (WCR): Alixorexton numerically improved weekly cataplexy rates across all doses compared to placebo at week six and achieved statistical significance at the 6 mg dose (p=0.005).
Alixorexton demonstrated consistent and clinically meaningful improvements across several patient-reported outcome measures of symptoms important to patients, including:
Narcolepsy Severity Scale (NSS): Across all doses tested, alixorexton demonstrated clinically meaningful improvements from baseline in narcolepsy symptom severity as compared to placebo at week six (p&lt;0.001 at all doses).
British Columbia Cognitive Complaints Inventory (BC-CCI): Across all doses tested, alixorexton demonstrated clinically meaningful improvements from baseline in cognitive complaints compared to placebo at week six (p&lt;0.0001 at all doses).
PROMIS (Patient-Reported Outcomes Measurement Information System)-Fatigue: Across all doses tested, alixorexton demonstrated clinically meaningful improvements from baseline in fatigue as compared to placebo at week six (p&lt;0.01 at all doses).
Alixorexton was generally well tolerated across all doses tested in the randomized double-blind period of the Vibrance-1 study.
No treatment-emergent serious adverse events (TEAEs) were reported. Most TEAEs were mild to moderate in severity and generally consistent with the events observed across the Alixorexton phase 1 program in healthy volunteers and patients.
No treatment-related safety signals were observed in hepatic and renal parameters, vital signs, or ophthalmic exams.
Vibrance-2 and Vibrance-3, phase 2 studies evaluating the safety and efficacy of alixorexton in adults with NT2 and IH, respectively, are ongoing.
In April 2024, Alkermes revealed topline results from the narcolepsy type 2 (NT2) and idiopathic hypersomnia (IH) cohorts of a phase 1b, proof-of-concept study evaluating&nbsp;<a target="_blank" href="https://www.benzinga.com/analyst-ratings/analyst-color/24/04/38170051/alkermes-sleeping-disorder-studies-data-look-excellent-analyst-says" rel="noreferrer noopener">ALKS 2680 for narcolepsy</a>.&nbsp;
ALKS 2680 data demonstrated clinically meaningful and statistically significant improvements from baseline in mean sleep latency on the Maintenance of Wakefulness Test compared to placebo at all doses tested.&nbsp;
Price Action: ALKS stock is trading lower by 7.24% to $27.11 at last check Monday.
Read Next:
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<li><a href="https://www.benzinga.com/markets/commodities/25/07/46514212/china-led-rally-sends-iron-ore-over-100-despite-looming-oversupply" target="_blank" rel="noreferrer noopener">China-Led Rally Sends Iron Ore Over $100 Despite Looming Oversupply</a></li>
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Photo via Shutterstock

Health Care

Movers

ALKS

Alkermes Oral Drug Helps Patients Stay Awake In Mid-Stage Sleep Disorder Study

D. Boral Capital analyst Jason Kolbert maintains CytoSorbents (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CTSO#NASDAQ">CTSO</a>) with a Buy and maintains $10 price target.

CTSO

D. Boral Capital Maintains Buy on CytoSorbents, Maintains $10 Price Target

D. Boral Capital analyst Jason Kolbert maintains Biomea Fusion (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BMEA#NASDAQ">BMEA</a>) with a Buy and maintains $16 price target.

BMEA

D. Boral Capital Maintains Buy on Biomea Fusion, Maintains $16 Price Target

<a href="https://www.cnbc.com/2025/07/21/jpmorgan-quantum-computing-leadership-state-street-exec.html" title="https://www.cnbc.com/2025/07/21/jpmorgan-quantum-computing-leadership-state-street-exec.html">https://www.cnbc.com/2025/07/21/jpmorgan-quantum-computing-leadership-state-street-exec.html</a>

'JPMorgan Chase Overhauls Quantum Computing Leadership, Poaches State Street Executive; Marco Pistoia, Who Became Head Of JPMorgan's Applied Research Group In 2020, Has Recently Left The Bank' - CNBC

The altcoin rally may only be getting started and follows the signing of the GENIUS Act, the most significant U.S. crypto legislation to date, ushering in <a href="https://www.benzinga.com/crypto/cryptocurrency/25/07/46508890/trump-signs-genius-act-ending-biden-era-crypto-probes-and-backing-industry-titans">structural clarity for digital assets</a>.
Speaking with Benzinga, Illia Otychenko, Lead Analyst at CEX.IO, identified three critical technical and on-chain signals driving the breakout.
"Net Taker Volume flipped positive, showing renewed buy-side aggression after months of seller dominance," Otychenko said. 
He also noted that long-term holders are moving from accumulation to distribution, a phase that has historically coincided with Bitcoin's steepest rallies.
Combined with a recent Golden Cross, where the 50-day moving average crossed above the 200-day, Otychenko said Bitcoin could see a short-term rise to $132,000 and as high as $170,000 by the end of Q3. 
These bullish indicators are consistent with earlier rally phases in the current cycle, including a 103% surge to $108,000 in January 2025.
Iliya Kalchev, analyst at Nexo Dispatch, echoed the sentiment, highlighting a sharp rotation from Bitcoin to Ethereum (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/eth/usd">ETH</a>) and select altcoins. 
Also Read: <a href="https://www.benzinga.com/crypto/cryptocurrency/25/07/46524833/ethereum-is-at-the-forefront-of-the-financial-services-revolution-bernstein-says">Ethereum Is At The Forefront Of The Financial Services Revolution, Bernstein Says</a>
"Ethereum is leading the charge, now at just under $3,800, up 1.6x since April," Kalchev said, adding that new institutional bids, like SharpLink Gaming's (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SBET#NASDAQ">SBET</a>) $6 billion ETH proposal, reinforce the asset's growing appeal as a balance sheet asset.
The GENIUS Act, signed into law last Friday, resolves longstanding regulatory friction in the U.S. 
It establishes clear rules for stablecoins, distinguishes asset classifications, and protects developers, prompting a broader investor reassessment of crypto exposure. 
The timing coincides with declining Bitcoin dominance and growing appetite for higher-beta assets such as ENA, XRP (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/xrp/usd">XRP</a>), Dogecoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/doge/usd">DOGE</a>), and Solana (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/sol/usd">SOL</a>).
The shifting capital landscape has sent ENA up 40% in a week, XRP past $3.50, and SOL near $191, with DOGE showing renewed strength in technical patterns and derivatives activity.
Cooper Research forecasts Bitcoin may hit $150,000 by October, buoyed by continued ETF inflows and macro tailwinds. 
Ethereum, meanwhile, could extend gains with analysts like Tom Lee of Fundstrat citing targets of $4,000 in the near term and $15,000 longer term.
At the same time, macro developments loom, including preliminary U.S. GDP data and flash PMIs, but traders remain focused on crypto's new regulatory footing and asset rotation themes.
Read Next: 
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<li><a href="https://www.benzinga.com/crypto/cryptocurrency/25/07/46520495/strategy-buys-6220-btc-boosts-bitcoin-war-chest-to-607770">Strategy Buys 6,220 BTC, Boosts Bitcoin War Chest To 607,770</a></li>
</ul>
Image: Shutterstock

Coverage of Bitcoin, Etherum, Ripple and all the latest digital currencies.

Cryptocurrency

$BTC

$DOGE

$ENA

$ETH

$SOL

$XRP

Ethereum, XRP, SOL Surge After GENIUS Act: What's Driving The Altcoin Rally?

<a href="https://www.bloomberg.com/news/articles/2025-07-21/fidji-simo-lays-out-vision-as-openai-ceo-of-applications-ahead-of-august-start">https://www.bloomberg.com/news/articles/2025-07-21/fidji-simo-lays-out-vision-as-openai-ceo-of-applications-ahead-of-august-start</a>

'Fidji Simo Lays Out Vision As OpenAI CEO of Applications Ahead of August Start'- Bloomberg

Telsey Advisory Group analyst Sarang Vora maintains Coursera (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/COUR#NYSE">COUR</a>) with a Outperform and maintains $12 price target.

COUR

Telsey Advisory Group Maintains Outperform on Coursera, Maintains $12 Price Target

A rare warning signal just reappeared in the market — and the last time it showed up, <a href="https://www.benzinga.com/topic/s-p-500">the S&amp;P 500 index</a> plunged more than 20% in a matter of weeks.
According to the <a href="https://www.aaii.com/latest/article/316918-aaii-sentiment-survey-pessimism-pushes-through">latest</a> AAII Sentiment Survey, the bull-bear spread has collapsed to just 0.3%, the lowest since September 2022 — right before the S&amp;P logged its steepest drop since the 2008 financial crisis.
That signal comes as bullish sentiment drops to 39.3% and bearish sentiment surges to 39.0%, a near-perfect split that reflects deep investor indecision. Neutral sentiment, meanwhile, remains depressed at 21.8%, well below its historical average of 31.5%. This extreme polarization often sets the stage for outsized volatility.
Read Also: <a href="https://www.benzinga.com/crypto/25/07/46526038/trump-bitcoin-gold-401k-retirement-funds-performance">Trump Wants Bitcoin And Gold In Your 401(k)—And The Math Backs Him Up</a>
<h2 class="wp-block-heading">Sentiment Deadlock Often Precedes Big Market Moves</h2>
When investors are evenly split, the market tends to lose its anchor. With neither bulls nor bears clearly in control, the S&amp;P 500 becomes vulnerable to fast and sharp moves. The last time the bull-bear spread hit such lows — in late 2022 — the index went on to suffer its worst annual loss since the global financial crisis.
Though current market levels remain elevated, the psychological backdrop has shifted. Investors are taking sides, not sitting out, and that often signals that something's about to give.
<h2 class="wp-block-heading">Positioning Around The Uncertainty</h2>
For those looking to stay invested while managing risk, ETFs such as SPDR S&amp;P 500 ETF Trust (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SPY#NYSE">SPY</a>) and Vanguard Total Stock Market ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/VTI#NYSE">VTI</a>) offer broad exposure. If tech optimism remains intact, Invesco QQQ ETF (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/QQQ#NASDAQ">QQQ</a>) provides leverage to growth themes.
For downside protection, low-volatility plays such as iShares MSCI USA Min Vol Factor ETF (BATS:<a class="ticker" href="https://www.benzinga.com/stock/USMV#BATS">USMV</a>) or dividend-focused funds like Vanguard Dividend Appreciation Index Fund ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/VIG#NYSE">VIG</a>) can help buffer shocks. Tactical investors expecting short-term pullbacks may also consider ProShares Short S&amp;P500 ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SH#NYSE">SH</a>) as a hedge.
Whether the signal leads to a repeat of 2022 or not, history suggests it's not one to ignore.
Read Next: 
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<li><a href="https://www.benzinga.com/etfs/sector-etfs/25/07/46524500/wall-street-meets-web3-fintech-etfs-spy-voo-to-get-jack-dorsey-upgrade-as-block-joins-sp-500">Wall Street Meets Web3: Fintech ETFs, SPY, VOO To Get Jack Dorsey Upgrade As Block Joins S&amp;P 500</a></li>
</ul>
Photo: Shutterstock

Long Ideas

Macro Economic Events

Broad U.S. Equity ETFs

Economics

Trading Ideas

ETFs

USMV

The Last Time This Warning Flashed, S&P 500 Crashed The Most Since 2008

WIIM

MFH stock has given up its prior gain. Mercurity Fintech shares were trading higher after the company announced it has entered into a $200 million equity line of credit agreement to launch a Solana-based treasury strategy.

Market Summary

Benzinga Market Summary: S&P Rises Amid Tech Strength, Gold Gains On Weaker Dollar, Cybersecurity Stocks Gain Amid SharePoint Hack

<a href="https://www.hhs.gov/press-room/hrsa-to-reform-organ-transplant-system.html#:~:text=It%20found%3A,serious%20ethical%20and%20legal%20questions" title="https://www.hhs.gov/press-room/hrsa-to-reform-organ-transplant-system.html#:~:text=It%20found%3A,serious%20ethical%20and%20legal%20questions">https://www.hhs.gov/press-room/hrsa-to-reform-organ-transplant-system.html#:~:text=It%20found%3A,serious%20ethical%20and%20legal%20questions</a>.

CDNA

TMDX

UTHR

'HHS Finds Systemic Disregard for Sanctity of Life in Organ Transplant System; To Begin Reforming Organ Transplant System; HRSA's Independent Investigation Revealed Clear Negligence After Previous OPTN Board Claimed To Find No Major Concerns In Internal Review'

CRWD

FTNT

PANW

SNOW

Shares of several cybersecurity-related stocks are trading higher amid a cyber attack on Microsoft's SharePoint servers.

Roth Capital analyst Rohit Kulkarni maintains Reddit (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/RDDT#NYSE">RDDT</a>) with a Neutral and raises the price target from $130 to $145.

RDDT

Roth Capital Maintains Neutral on Reddit, Raises Price Target to $145

CGAU

PAAS

RGLD

SSRM

USAU

Shares of precious metal-related stocks are trading higher amid tariff uncertainty, which has weakened the US dollar and bond yields.

Press Releases

Panbela to Host Second Quarter 2024 Earnings Conference Call on Aug 13, 2024

Earnings

Panbela Provides Business Update and Reports Q2 2024 Financial Results

First Patient Enrolled in Phase I Program in STK11 Mutant Non-Small Cell Lung Cancer at Moffitt Cancer Center

Panbela to Host Third Quarter 2024 Earnings Conference Call on November 14, 2024

Comments

Panbela Therapeutics

Vendite allo scoperto

Panbela Therapeutics (OTC:PBLA) Azioni, Report sulle vendite allo scoperto

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