| Oct 1, 2026 | Heidy King-Jones | SEE REMARKS | SELL-OPTIONS | — | $52.77 | $2.2M |
| Oct 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $92.01 | $1.4M |
| Sep 30, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $52.49 | $1.9M |
| Sep 1, 2026 | Heidy King-Jones | SEE REMARKS | SELL-OPTIONS | — | $50.92 | $2.1M |
| Sep 1, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL | 18.232K | $51.63 | $2.2M |
| Sep 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $87.29 | $1.3M |
| Aug 7, 2026 | Jeffrey Albers | DIRECTOR | SELL | 18.000K | $57.46 | $2.4M |
| Aug 3, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $55.03 | $608K |
| Aug 3, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $95.51 | $1.4M |
| Jul 1, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $51.12 | $549K |
| Jul 1, 2026 | Sheldon Sloan | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $57.58 | $502K |
| Jul 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $87.69 | $1.3M |
| Jun 25, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $50.82 | $1.1M |
| Jun 23, 2026 | Fairmount Funds Management LLC, Fairmount Healthcare Fund II LP, Tomas Kiselak, Evan Peter Harwin | DIRECTOR | SELL | 4.018M | $85.31 | $399.7M |
| Jun 22, 2026 | THOMAS MICHAEL HENDERSON | DIRECTOR | SELL | 20.000K | $100.00 | $2.0M |
| Jun 3, 2026 | Sheldon Sloan | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $51.23 | $396K |
| Jun 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $70.43 | $1.1M |
| Jun 1, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $42.78 | $424K |
| May 8, 2026 | THOMAS MICHAEL HENDERSON | DIRECTOR | SELL | 80.000K | $74.40 | $6.0M |
| May 1, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $42.94 | $711K |
| May 1, 2026 | Sheldon Sloan | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $49.48 | $3.4M |
| May 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $71.37 | $1.1M |
