Bulls vs Bears
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$90.33
-2.00-2.17%
Ult. Agg.: Oct 23, 4:28 PM
Market sentiment signals for Spyre Therapeutics (SYRE): analyst consensus, short interest, options flow and insider activity.
Analyst Consensus
Buy
20 analysts
Options Flow (P/C)
—
Avg Consensus PT
$101
+11.7%
Highest Price Target
$130
+43.9%
Lowest Price Target
$44
-51.3%
Short Interest
14.6%
Declining — Bullish
Insider Activity (30d)
Net Seller
Short Interest — % of Float
| Date | Firm | Analyst & Accuracy | Upside / Downside | PT Change | Action | Rating |
|---|---|---|---|---|---|---|
| Oct 19, 2026 | BTIG | Julian Harrison— | +34.0% | $121 → $121 | Maintained | Buy |
| Oct 12, 2026 | UBS | Alice Nettleton— | +32.8% | $120 | Initiate | Buy |
